| ERM, Ezrin/radixin/moesin family. This family of proteins contain a band 4.1 domain (pfam00373), at their amino terminus. This family represents the rest of these proteins | 336 genes |
| electron transport, IEA | 268 genes |
| extracellular space, TAS | 189 genes |
| extracellular, IEA | 185 genes |
| endoplasmic reticulum, IEA | 174 genes |
| extracellular, NAS | 170 genes |
| EzrA, Septation ring formation regulator, EzrA. During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerises into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequ | 147 genes |
| extracellular matrix, IEA | 87 genes |
| electron transporter activity, IEA | 81 genes |
| electron transporter activity, TAS | 79 genes |
| extracellular space, NR | 73 genes |
| endoplasmic reticulum, TAS | 71 genes |
| extracellular, TAS | 62 genes |
| energy pathways, TAS | 57 genes |
| epidermis development, TAS | 56 genes |
| endocytosis, IEA | 50 genes |
| Extensin_2, Extensin-like region | 43 genes |
| extracellular ligand-gated ion channel activity, IEA | 41 genes |
| extracellular matrix, TAS | 39 genes |
| endonuclease activity, IEA | 35 genes |
| E-MAP-115, E-MAP-115 family. The organisation of microtubules varies with the cell type and is presumably controlled by tissue-specific microtubule-associated proteins (MAPs). The 115-kDa epithelial MAP (E-MAP-115) has been identified as a mic | 34 genes |
| energy pathways, NR | 30 genes |
| E1-E2_ATPase, E1-E2 ATPase | 29 genes |
| Ets, Ets-domain | 29 genes |
| excretion, TAS | 28 genes |
| Exo_endo_phos, Endonuclease/Exonuclease/phosphatase family. This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signalling. This family includes: AP endonuclease | 26 genes |
| eIF-4B, Plant specific eukaryotic initiation factor 4B. This family consists of several plant specific eukaryotic initiation factor 4B proteins | 26 genes |
| extracellular matrix structural constituent, IEA | 26 genes |
| extracellular matrix structural constituent, NAS | 24 genes |
| endosome, TAS | 23 genes |
| EGF, EGF-like domain. There is no clear separation between noise and signal. pfam00053 is very similar, but has 8 instead of 6 conserved cysteines. Includes some cytokine receptors | 22 genes |
| exonuclease activity, IEA | 22 genes |
| extracellular matrix, NAS | 22 genes |
| efhand, EF hand. The EF-hands can be divided into two classes: signaling proteins and buffering/transport proteins. The first group is the largest and includes the most well-known members of the family such as calmodulin, troponin C and S100B. | 21 genes |
| extracellular matrix structural constituent, TAS | 21 genes |
| enzyme activator activity, TAS | 20 genes |
| Ebola_NP, Ebola nucleoprotein. This family consists of Ebola and Marburg virus nucleoproteins. These proteins are responsible for encapsidation of genomic RNA. It has been found that nucleoprotein DNA vaccines can offer protection from the vir | 19 genes |
| extracellular, NR | 18 genes |
| ECH, Enoyl-CoA hydratase/isomerase family. This family contains a diverse set of enzymes including: Enoyl-CoA hydratase. Napthoate synthase. Carnitate racemase. 3-hydoxybutyryl-CoA dehydratase. Dodecanoyl-CoA delta-isomerase | 17 genes |
| electron transporter activity, NR | 17 genes |
| endopeptidase activity, IEA | 16 genes |
| extracellular matrix, NR | 16 genes |
| endoplasmic reticulum membrane, TAS | 16 genes |
| Exonuc_X-T, Exonuclease. This family includes a variety of exonuclease proteins, such as ribonuclease T and the epsilon subunit of DNA polymerase III | 15 genes |
| Epimerase, NAD dependent epimerase/dehydratase family. This family of proteins utilise NAD as a cofactor. The proteins in this family use nucleotide-sugar substrates for a variety of chemical reactions | 15 genes |
| extracellular, IDA | 15 genes |
| Ephrin_lbd, Ephrin receptor ligand binding domain. The Eph receptors, which bind to ephrins pfam00812 are a large family of receptor tyrosine kinases. This family represents the amino terminal domain which binds the ephrin ligand | 14 genes |
| enzyme inhibitor activity, TAS | 14 genes |
| E2F_TDP, Transcription factor E2F/dimerisation partner (TDP). This family contains the transcription factor E2F and its dimerisation partners TDP1 and TDP2, which stimulate E2F-dependent transcription. E2F binds to DNA as a homodimer or as a h | 13 genes |
| electron carrier activity, TAS | 12 genes |
| extracellular matrix structural constituent, NR | 11 genes |
| electron transport, NAS | 11 genes |
| electron transport, TAS | 11 genes |
| EMP24_GP25L, emp24/gp25L/p24 family. Members of this family are implicated in bringing cargo forward from the ER and binding to coat proteins by their cytoplasmic domains | 10 genes |
| ELM2, ELM2 domain. The ELM2 (Egl-27 and MTA1 homology 2) domain is a small domain of unknown function. It is found in the MTA1 protein that is part of the NuRD complex. The domain is usually found to the N terminus of a myb-like DNA binding do | 10 genes |
| eIF-3c_N, Eukaryotic translation initiation factor 3 subunit 8 N-terminus (eIF3c_N). The largest of the mammalian translation initiation factors, eIF3, consists of at least eight subunits ranging in mass from 35 to 170 kDa. eIF3 binds to the 4 | 10 genes |
| ephrin receptor activity, IEA | 10 genes |
| exocytosis, TAS | 10 genes |
| endocytosis, TAS | 10 genes |
| establishment and/or maintenance of cell polarity, TAS | 10 genes |
| enzyme binding, IPI | 10 genes |
| E1_dh, Dehydrogenase E1 component. This family uses thiamine pyrophosphate as a cofactor. This family includes pyruvate dehydrogenase, 2-oxoglutarate dehydrogenase and 2-oxoisovalerate dehydrogenase | 9 genes |
| ENTH, ENTH domain. The ENTH (Epsin N-terminal homology) domain is found in proteins involved in endocytosis and cytoskeletal machinery. The function of the ENTH domain is unknown | 9 genes |
| endoplasmic reticulum, NAS | 9 genes |
| endoplasmic reticulum, NR | 9 genes |
| exocytosis, IEA | 9 genes |
| ER to Golgi transport, TAS | 9 genes |
| epidermal growth factor receptor signaling pathway, TAS | 9 genes |
| ectoderm development, TAS | 9 genes |
| embryonic development, ISS | 9 genes |
| Ephrin, Ephrin | 8 genes |
| extracellular space, NAS | 8 genes |
| eukaryotic translation initiation factor 3 complex, TAS | 8 genes |
| establishment and/or maintenance of chromatin architecture, NAS | 8 genes |
| endocytosis, NAS | 8 genes |
| extrinsic to membrane, TAS | 8 genes |
| enzyme binding, NAS | 8 genes |
| ELO, GNS1/SUR4 family. Members of this family are involved in long chain fatty acid elongation systems that produce the 26-carbon precursors for ceramide and sphingolipid synthesis. Predicted to be integral membrane proteins, in eukaryotes the | 7 genes |
| extracellular, IC | 7 genes |
| extracellular, ISS | 7 genes |
| ER to Golgi transport, NAS | 7 genes |
| Endonuclease_NS, DNA/RNA non-specific endonuclease | 6 genes |
| EMP70, Endomembrane protein 70 | 6 genes |
| ETS_PEA3_N, PEA3 subfamily ETS-domain transcription factor N terminus. The N terminus of the PEA3 transcription factors is implicated in transactivation and in inhibition of DNA binding. Transactivation is potentiated by activation of the Ras/ | 6 genes |
| embryonic development (sensu Mammalia), ISS | 6 genes |
| enoyl-CoA hydratase activity, TAS | 6 genes |
| endopeptidase inhibitor activity, TAS | 6 genes |
| establishment and/or maintenance of chromatin architecture, TAS | 6 genes |
| endosome transport, NAS | 6 genes |
| eukaryotic translation initiation factor 4F complex, TAS | 6 genes |
| extracellular matrix organization and biogenesis, NAS | 6 genes |
| EFG_C, Elongation factor G C-terminus. This domain includes the carboxyl terminal regions of Elongation factor G, elongation factor 2 and some tetracycline resistance proteins and adopt a ferredoxin-like fold | 5 genes |
| EF1_GNE, EF-1 guanine nucleotide exchange domain. This family is the guanine nucleotide exchange domain of EF-1 beta and EF-1 delta chains | 5 genes |
| Esterase, Putative esterase. This family contains Esterase D. However it is not clear if all members of the family have the same function. This family is related to the pfam00135 family | 5 genes |
| EPTP, EPTP domain. Mutations in the LGI/Epitempin gene can result in a special form of epilepsy, autosomal dominant lateral temporal epilepsy. The Epitempin protein contains a large repeat in its C terminal section. This presumed domain has no | 5 genes |
| Endosulfine, cAMP-regulated phosphoprotein/endosulfine conserved region. Conserved region found in both cAMP-regulated phosphoprotein 19 (ARPP-19) and Alpha/Beta endosulfine. No function has yet been assigned to ARPP-19. Endosulfine is the end | 5 genes |
| endopeptidase inhibitor activity, IEA | 5 genes |
| epidermal growth factor receptor activity, IEA | 5 genes |
| extracellular matrix, ISS | 5 genes |
| extracellular space, IEA | 5 genes |
| endosome, NR | 5 genes |
| early endosome, IDA | 5 genes |
| endoplasmic reticulum membrane, IDA | 5 genes |
| energy reserve metabolism, TAS | 5 genes |
| embryo implantation, TAS | 5 genes |
| enzyme activator activity, IEA | 5 genes |
| enzyme activator activity, NR | 5 genes |
| embryonic development, NAS | 5 genes |
| enzyme binding, ISS | 5 genes |
| ephrin receptor binding, TAS | 5 genes |
| Enolase_C, Enolase, C-terminal TIM barrel domain | 4 genes |
| eIF-5a, Eukaryotic initiation factor 5A hypusine, DNA-binding OB fold | 4 genes |
| Exostosin, Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses | 4 genes |
| EFG_IV, Elongation factor G, domain IV. This domain is found in elongation factor G, elongation factor 2 and some tetracycline resistance proteins and adopts a ribosomal protein S5 domain 2-like fold | 4 genes |
| EspF, EspF protein. The enteropathogenic Escherichia coli EspF secreted protein induces host cell apoptosis. Its proline-rich structure suggests that it may act by binding to SH3 domains or EVH1 domains of host cell signalling proteins | 4 genes |
| EI24, Etoposide-induced protein 2.4 (EI24). This family contains a number of eukaryotic etoposide-induced 2.4 (EI24) proteins approximately 350 residues long. In cells treated with the cytotoxic drug etoposide, EI24 is induced by p53. It has b | 4 genes |
| exocyst, IEA | 4 genes |
| exosome (RNase complex), IEA | 4 genes |
| estradiol 17-beta-dehydrogenase activity, IEA | 4 genes |
| endodeoxyribonuclease activity, TAS | 4 genes |
| endoplasmic reticulum lumen, TAS | 4 genes |
| endoplasmic reticulum membrane, ISS | 4 genes |
| endoplasmic reticulum membrane, NR | 4 genes |
| ethanol oxidation, TAS | 4 genes |
| electron transport, IDA | 4 genes |
| eye pigment biosynthesis, TAS | 4 genes |
| embryonic development, IEA | 4 genes |
| endocytic vesicle, TAS | 4 genes |
| embryonic limb morphogenesis, ISS | 4 genes |
| estrogen receptor signaling pathway, NAS | 4 genes |
| Endothelin, Endothelin family | 3 genes |
| ER_lumen_recept, ER lumen protein retaining receptor | 3 genes |
| eIF-1a, Eukaryotic initiation factor 1A | 3 genes |
| ERG4_ERG24, Ergosterol biosynthesis ERG4/ERG24 family | 3 genes |
| E1_DerP2_DerF2, ML domain. ML domain - MD-2-related lipid recognition domain. This family consists of proteins from plants, animals and fungi, including dust mite allergen Der P 2. It has been implicate in lipid recognition, particularly in th | 3 genes |
| ERCC4, ERCC4 domain. This domain is predicted to be a nuclease domain | 3 genes |
| E3_binding, e3 binding domain. This family represents a small domain of the E2 subunit of 2-oxo-acid dehydrogenases responsible for the binding of the E3 subunit | 3 genes |
| EB1, EB1-like C-terminal motif. This motif is found at the C-terminus of proteins that are related to the EB1 protein. The EB1 proteins contain an N-terminal CH domain pfam00307. The human EB1 protein was originally discovered as a protein int | 3 genes |
| Enolase_N, Enolase, N-terminal domain | 3 genes |
| Evr1_Alr, Erv1 / Alr family. Biogenesis of Fe/S clusters involves a number of essential mitochondrial proteins. Erv1p of Saccharomyces cerevisiae mitochondria is required for the maturation of Fe/S proteins in the cytosol. The ALR (augmenter o | 3 genes |
| eIF_4EBP, Eukaryotic translation initiation factor 4E binding protein (EIF4EBP). This family consists of several eukaryotic translation initiation factor 4E binding proteins (EIF4EBP1 ,2 and 3). Translation initiation in eukaryotes is mediated | 3 genes |
| ECM1, Extracellular matrix protein 1 (ECM1). This family consists of several eukaryotic extracellular matrix protein 1 (ECM1) sequences. ECM1 has been shown to regulate endochondral bone formation, stimulate the proliferation of endothelial ce | 3 genes |
| Elongin_A, RNA polymerase II transcription factor SIII (Elongin) subunit A. This family represents a conserved region within RNA polymerase II transcription factor SIII (Elongin) subunit A. In mammals, the Elongin complex activates elongation | 3 genes |
| eye morphogenesis (sensu Mammalia), TAS | 3 genes |
| epsilon DNA polymerase activity, TAS | 3 genes |
| endonuclease activity, NAS | 3 genes |
| endonuclease activity, TAS | 3 genes |
| epidermal growth factor receptor binding, TAS | 3 genes |
| endosome, IDA | 3 genes |
| endosome, NAS | 3 genes |
| endoplasmic reticulum membrane, IEA | 3 genes |
| eukaryotic translation elongation factor 1 complex, IEA | 3 genes |
| establishment of tissue polarity, TAS | 3 genes |
| eukaryotic initiation factor 4E binding, IEA | 3 genes |
| endosome to lysosome transport, TAS | 3 genes |
| epidermis development, NAS | 3 genes |
| energy derivation by oxidation of organic compounds, TAS | 3 genes |
| enzyme binding, TAS | 3 genes |
| estrogen receptor signaling pathway, ISS | 3 genes |
| epithelial cell differentiation, ISS | 3 genes |
| extrinsic to plasma membrane, GPI-anchored, ISS | 3 genes |
| EPO_TPO, Erythropoietin/thrombopoietin | 2 genes |
| eIF-5_eIF-2B, Domain found in IF2B/IF5. This family includes the N terminus of eIF-5, and the C terminus of eIF-2 beta. This region corresponds to the whole of the archaebacterial eIF-2 beta homologue. The region contains a putative zinc bindi | 2 genes |
| Exonuc_VII_L, Exonuclease VII, large subunit. This family consist of exonuclease VII, large subunit EC:3.1.11.6 This enzyme catalyses exonucleolytic cleavage in either 5'->3' or 3'->5' direction to yield 5'-phosphomononucleotides. This exonucl | 2 genes |
| eRF1_1, eRF1 domain 1. The release factor eRF1 terminates protein biosynthesis by recognising stop codons at the A site of the ribosome and stimulating peptidyl-tRNA bond hydrolysis at the peptidyl transferase centre. The crystal structure of | 2 genes |
| eRF1_2, eRF1 domain 2. The release factor eRF1 terminates protein biosynthesis by recognising stop codons at the A site of the ribosome and stimulating peptidyl-tRNA bond hydrolysis at the peptidyl transferase centre. The crystal structure of | 2 genes |
| eRF1_3, eRF1 domain 3. The release factor eRF1 terminates protein biosynthesis by recognising stop codons at the A site of the ribosome and stimulating peptidyl-tRNA bond hydrolysis at the peptidyl transferase centre. The crystal structure of | 2 genes |
| ERO1, Endoplasmic Reticulum Oxidoreductin 1 (ERO1). Members of this family are required for the formation of disulphide bonds in the ER | 2 genes |
| eIF-3_zeta, Eukaryotic translation initiation factor 3 subunit 7 (eIF-3). This family is made up of eukaryotic translation initiation factor 3 subunit 7 (eIF-3 zeta/eIF3 p66/eIF3d). Eukaryotic initiation factor 3 is a multi-subunit complex tha | 2 genes |
| EBP, Emopamil binding protein. Emopamil binding protein (EBP) is as a gene that encodes a nonglycosylated type I integral membrane protein of endoplasmic reticulum and shows high level expression in epithelial tissues. The EBP protein has emop | 2 genes |
| Ebp2, Eukaryotic rRNA processing protein EBP2. This family consists of several Eukaryotic rRNA processing protein EBP2 sequences. Ebp2p is required for the maturation of 25S rRNA and 60S subunit assembly. Ebp2p may be one of the target protein | 2 genes |
| eIF-3_p25, Eukaryotic translation initiation factor 3 subunit 11 (eIF-3 p25). This family consists of several eukaryotic translation initiation factor 3 subunit 11 (eIF-3 p25) proteins. Eukaryotic initiation factor 3 (eIF3) is a multisubunit c | 2 genes |
| Endostatin, Collagenase NC10 and Endostatin. NC10 stands for Non-helical region 10. A mutation in this region in Collagen alpha 1(XVIII) precursor is associated with an increased risk of prostate cancer. This domain is cleaved from the precurs | 2 genes |
| E_Pc_C, Enhancer of Polycomb C-terminus. This family represents the C-terminus of eukaryotic enhancer of polycomb proteins, which have roles in heterochromatin formation. This family contains several conserved motifs | 2 genes |
| exosome (RNase complex), TAS | 2 genes |
| electron-transferring-flavoprotein dehydrogenase activity, TAS | 2 genes |
| endopeptidase activity, TAS | 2 genes |
| estradiol 17-beta-dehydrogenase activity, NAS | 2 genes |
| estradiol 17-beta-dehydrogenase activity, TAS | 2 genes |
| ethanolaminephosphotransferase activity, TAS | 2 genes |
| exo-alpha-sialidase activity, IEA | 2 genes |
| enzyme inhibitor activity, IEA | 2 genes |
| enzyme inhibitor activity, ISS | 2 genes |
| ErbB-2 class receptor binding, TAS | 2 genes |
| extracellular ligand-gated ion channel activity, NAS | 2 genes |
| extracellular, IEP | 2 genes |
| early endosome, ISS | 2 genes |
| early endosome, TAS | 2 genes |
| endoplasmic reticulum lumen, ISS | 2 genes |
| ER-Golgi intermediate compartment, TAS | 2 genes |
| eukaryotic translation initiation factor 2 complex, TAS | 2 genes |
| eukaryotic translation initiation factor 2B complex, IEA | 2 genes |
| eukaryotic translation initiation factor 2B complex, NAS | 2 genes |
| energy pathways, NAS | 2 genes |
| establishment and/or maintenance of chromatin architecture, ISS | 2 genes |
| estrogen biosynthesis, IEA | 2 genes |
| exocytosis, NAS | 2 genes |
| exocytosis, NR | 2 genes |
| ER to Golgi transport, IEA | 2 genes |
| ER to Golgi transport, NR | 2 genes |
| endocytosis, IDA | 2 genes |
| endocytosis, NR | 2 genes |
| epidermal growth factor receptor signaling pathway, ISS | 2 genes |
| epidermal growth factor receptor signaling pathway, NAS | 2 genes |
| endoderm development, TAS | 2 genes |
| excretion, NR | 2 genes |
| estrogen metabolism, TAS | 2 genes |
| external side of plasma membrane, IDA | 2 genes |
| energy coupled proton transport, against electrochemical gradient, IEA | 2 genes |
| endosome transport, TAS | 2 genes |
| endothelin-converting enzyme 1 activity, IEA | 2 genes |
| extracellular matrix structural constituent conferring tensile strength, NAS | 2 genes |
| extracellular matrix constituent conferring elasticity, NAS | 2 genes |
| extracellular matrix constituent, lubricant activity, NAS | 2 genes |
| extracellular matrix organization and biogenesis, IEA | 2 genes |
| erythrocyte differentiation, NAS | 2 genes |
| enzyme regulator activity, IEA | 2 genes |
| estrogen receptor activity, TAS | 2 genes |
| estrogen receptor binding, NAS | 2 genes |
| estrogen receptor signaling pathway, IDA | 2 genes |
| exogenous peptide antigen binding, NAS | 2 genes |
| establishment and/or maintenance of epithelial cell polarity, ISS | 2 genes |
| endothelial cell differentiation, NAS | 2 genes |
| extrinsic to plasma membrane, GPI-anchored, TAS | 2 genes |
| enhancement of virulence, TAS | 2 genes |
| EF1G, Elongation factor 1 gamma, conserved domain | 1 genes |
| ETF_alpha, Electron transfer flavoprotein alpha subunit. This protein is distantly related to and forms a heterodimer with pfam01012 | 1 genes |
| Ependymin, Ependymin | 1 genes |
| EF_TS, Elongation factor TS | 1 genes |
| ETF_beta, Electron transfer flavoprotein beta subunit. This protein is distantly related to and forms a heterodimer with pfam00766 | 1 genes |
| ER, Enhancer of rudimentary. Enhancer of rudimentary is a protein of unknown function that is highly conserved in plants and animals. This protein is found to be an enhancer of the rudimentary gene | 1 genes |
| eIF-6, eIF-6 family. This family includes eukaryotic translation initiation factor 6 as well as presumed archaebacterial homologues | 1 genes |
| Epimerase_2, UDP-N-acetylglucosamine 2-epimerase. This family consists of UDP-N-acetylglucosamine 2-epimerases EC:5.1.3.14 this enzyme catalyses the production of UDP-ManNAc from UDP-GlcNAc. Note that some of the enzymes is this family are bif | 1 genes |
| Exo70, Exo70 exocyst complex subunit. The Exo70 protein forms one subunit of the exocyst complex. First discovered in S. cerevisiae, Exo70 and other exocyst proteins have been observed in several other eukaryotes, including humans. In S. cerev | 1 genes |
| EXS, EXS family. We have named this region the EXS family after (ERD1, XPR1, and SYG1). This family includes C-terminus portions from the SYG1 G-protein associated signal transduction protein from Saccharomyces cerevisiae, and sequences that a | 1 genes |
| Erg28, Erg28 like protein. This is a family of integral membrane proteins, which may contain four transmembrane helices. Members of this family are thought to be involved in sterol C-4 demethylation. In S. cerevisiae they may tether Erg26p (st | 1 genes |
| ENT, ENT domain. This presumed domain is named after Emsy N Terminus (ENT). Emsy is a protein that is amplified in breast cancer and interacts with BRCA2. The N terminus of this protein is found to be similar to other vertebrate and plant prot | 1 genes |
| Exportin-t, Exportin-t. Exportin-t is a specific mediator of tRNA export. RanGTP-binding, importin beta-related factor with predominantly nuclear localisation. It shuttles rapidly between nucleus and between nucleus and cytoplasm and interacts | 1 genes |
| EAP30, EAP30. EAP30 is a subunit of the ELL complex. The ELL is an 80-kDa RNA polymerase II transcription factor. ELL interacts with three other proteins to form the complex known as ELL complex. The ELL complex is capable of increasing that c | 1 genes |
| eIF3_gamma, Eukaryotic initiation factor 3, gamma subunit. eIF-3 is a multi-subunit complex that stimulates translation initiation in vitro at several different steps. This family corresponds to the gamma subunit if eIF3 | 1 genes |
| Endonuclease_5, Endonuclease V. Endonuclease V is specific for single-stranded DNA or for duplex DNA that contains uracil or that is damaged by a variety of agents | 1 genes |
| ERG2_Sigma1R, ERG2 and Sigma1 receptor like protein. This family consists of the fungal C-8 sterol isomerase and mammalian sigma1 receptor. C-8 sterol isomerase (delta-8--delta-7 sterol isomerase), catalyses a reaction in ergosterol biosynthes | 1 genes |
| ETC_C1_NDUFA5, ETC complex I subunit conserved region. Family of eukaryotic NADH-ubiquinone oxidoreductase subunits (EC:1.6.5.3) (EC:1.6.99.3) from complex I of the electron transport chain initially identified in Neurospora crassa as a 29.9 k | 1 genes |
| ETC_C1_NDUFA4, ETC complex I subunit conserved region. Family of pankaryotic NADH-ubiquinone oxidoreductase subunits (EC:1.6.5.3) (EC:1.6.99.3) from complex I of the electron transport chain initially identified in Neurospora crassa as a 21 kD | 1 genes |
| ETF_QO, Electron transfer flavoprotein-ubiquinone oxidoreductase. Electron-transfer flavoprotein-ubiquinone oxidoreductase (ETF-QO) in the inner mitochondrial membrane accepts electrons from electron-transfer flavoprotein which is located in t | 1 genes |
| EVI2A, Ectropic viral integration site 2A protein (EVI2A). This family contains several mammalian ectropic viral integration site 2A (EVI2A) proteins. The function of this protein is unknown although it is thought to be a membrane protein and | 1 genes |
| EB1_binding, EB-1 Binding Domain. This region at the C-terminus of the APC proteins binds the microtubule-associating protein EB-1. At the C-terminus of the alignment is also a pfam00595 binding domain. A short motif in the middle of the regio | 1 genes |
| ECSIT, ECSIT (evolutionarily conserved signaling intermediate in Toll pathways). Activation of NF-kappaB as a consequence of signaling through the Toll and IL-1 receptors is a major element of innate immune responses. ECSIT plays an important | 1 genes |
| EHN, Epoxide hydrolase N terminus. This family represents the N-terminal region of the eukaryotic epoxide hydrolase protein. Epoxide hydrolases (EC:3.3.2.3) comprise a group of functionally related enzymes that catalyse the addition of water t | 1 genes |
| EURL, EURL protein. This family consists of several animal EURL proteins. EURL is preferentially expressed in chick retinal precursor cells as well as in the anterior epithelial cells of the lens at early stages of development. EURL transcript | 1 genes |
| Endomucin, Endomucin. This family consists of several mammalian endomucin proteins. Endomucin is an early endothelial-specific antigen that is also expressed on putative hematopoietic progenitor cells | 1 genes |
| exocyst, NAS | 1 genes |
| euchromatin, IDA | 1 genes |
| euchromatin, ISS | 1 genes |
| endothelin-A receptor activity, NAS | 1 genes |
| embryonic development (sensu Mammalia), IEP | 1 genes |
| embryonic development (sensu Mammalia), NAS | 1 genes |
| eye morphogenesis (sensu Mammalia), NAS | 1 genes |
| epsilon DNA polymerase activity, NAS | 1 genes |
| electron-transferring-flavoprotein dehydrogenase activity, IEA | 1 genes |
| electron-transferring-flavoprotein dehydrogenase activity, ISS | 1 genes |
| endopeptidase activity, NAS | 1 genes |
| enteropeptidase activity, IEA | 1 genes |
| epoxide hydrolase activity, IDA | 1 genes |
| epoxide hydrolase activity, NAS | 1 genes |
| epoxide hydrolase activity, NR | 1 genes |
| epoxide hydrolase activity, TAS | 1 genes |
| estrone sulfotransferase activity, TAS | 1 genes |
| ethanolamine kinase activity, IDA | 1 genes |
| ethanolamine kinase activity, IEA | 1 genes |
| ethanolamine-phosphate cytidylyltransferase activity, TAS | 1 genes |
| exo-alpha-sialidase activity, TAS | 1 genes |
| endonuclease activity, NR | 1 genes |
| endodeoxyribonuclease activity, NR | 1 genes |
| endoribonuclease activity, IEA | 1 genes |
| endoribonuclease activity, NAS | 1 genes |
| endoribonuclease activity, TAS | 1 genes |
| exonuclease activity, TAS | 1 genes |
| eukaryotic translation initiation factor 2alpha kinase activity, IDA | 1 genes |
| eukaryotic translation initiation factor 2alpha kinase activity, TAS | 1 genes |
| enzyme inhibitor activity, NR | 1 genes |
| endopeptidase inhibitor activity, NR | 1 genes |
| erythropoietin receptor activity, TAS | 1 genes |
| endothelin receptor activity, NAS | 1 genes |
| endothelin receptor activity, TAS | 1 genes |
| ephrin receptor activity, TAS | 1 genes |
| epidermal growth factor receptor activity, NR | 1 genes |
| epidermal growth factor receptor activity, TAS | 1 genes |
| erythropoietin receptor binding, NR | 1 genes |
| epidermal growth factor receptor binding, IPI | 1 genes |
| epidermal growth factor receptor activating ligand activity, NR | 1 genes |
| epidermal growth factor receptor activating ligand activity, TAS | 1 genes |
| ErbB-2 class receptor binding, ISS | 1 genes |
| eye pigment precursor transporter activity, NR | 1 genes |
| electron transporter activity, IDA | 1 genes |
| electron transporter activity, NAS | 1 genes |
| extracellular space, IC | 1 genes |
| extracellular space, ISS | 1 genes |
| endosome, ISS | 1 genes |
| early endosome, NAS | 1 genes |
| endoplasmic reticulum, IDA | 1 genes |
| endoplasmic reticulum, ISS | 1 genes |
| endoplasmic reticulum lumen, IDA | 1 genes |
| endoplasmic reticulum lumen, IMP | 1 genes |
| endoplasmic reticulum lumen, NAS | 1 genes |
| endoplasmic reticulum lumen, NR | 1 genes |
| endoplasmic reticulum membrane, NAS | 1 genes |
| eukaryotic translation initiation factor 2 complex, ISS | 1 genes |
| eukaryotic translation initiation factor 2 complex, NR | 1 genes |
| eukaryotic translation elongation factor 1 complex, NAS | 1 genes |
| eukaryotic translation elongation factor 1 complex, TAS | 1 genes |
| ethanol oxidation, NR | 1 genes |
| energy pathways, IEA | 1 genes |
| energy reserve metabolism, ISS | 1 genes |
| ergosterol biosynthesis, IEA | 1 genes |
| estrogen biosynthesis, NAS | 1 genes |
| estrogen biosynthesis, NR | 1 genes |
| estrogen catabolism, IDA | 1 genes |
| extracellular transport, NR | 1 genes |
| exocytosis, ISS | 1 genes |
| ER to Golgi transport, ISS | 1 genes |
| endosome organization and biogenesis, NAS | 1 genes |
| establishment and/or maintenance of cell polarity, IMP | 1 genes |
| establishment and/or maintenance of cell polarity, ISS | 1 genes |
| enzyme linked receptor protein signaling pathway, ISS | 1 genes |
| epidermal growth factor receptor signaling pathway, NR | 1 genes |
| eye morphogenesis (sensu Drosophila), TAS | 1 genes |
| ectoderm and mesoderm interaction, TAS | 1 genes |
| excretion, NAS | 1 genes |
| establishment of blood/nerve barrier, TAS | 1 genes |
| exopeptidase activity, TAS | 1 genes |
| endosome to lysosome transport, NAS | 1 genes |
| endopeptidase Clp activity, IEA | 1 genes |
| endopeptidase Clp activity, TAS | 1 genes |
| epsilon DNA polymerase complex, NAS | 1 genes |
| exodeoxyribonuclease III activity, IEA | 1 genes |
| electron donor activity, NAS | 1 genes |
| electron donor activity, NR | 1 genes |
| electron acceptor activity, TAS | 1 genes |
| entrainment of circadian clock, NAS | 1 genes |
| entrainment of circadian clock, TAS | 1 genes |
| embryonic development, IMP | 1 genes |
| embryonic development, TAS | 1 genes |
| external side of plasma membrane, NAS | 1 genes |
| endosome membrane, NAS | 1 genes |
| endomembrane system, ISS | 1 genes |
| electrochemical potential-driven transporter activity, NAS | 1 genes |
| energy derivation by oxidation of organic compounds, NAS | 1 genes |
| eta DNA polymerase activity, TAS | 1 genes |
| endosome transport, IMP | 1 genes |
| eukaryotic translation initiation factor 4F complex, IDA | 1 genes |
| eukaryotic translation initiation factor 4F complex, NAS | 1 genes |
| eukaryotic translation initiation factor 4F complex, NR | 1 genes |
| extrinsic to membrane, NAS | 1 genes |
| extrinsic to membrane, NR | 1 genes |
| establishment of cell polarity, ISS | 1 genes |
| establishment of cell polarity, NAS | 1 genes |
| ER-Golgi transport vesicle, NAS | 1 genes |
| extracellular matrix organization and biogenesis, ISS | 1 genes |
| erythrocyte differentiation, IEP | 1 genes |
| estrogen receptor activity, NAS | 1 genes |
| embryonic limb morphogenesis, NAS | 1 genes |
| estrogen receptor binding, IDA | 1 genes |
| estrogen receptor binding, IPI | 1 genes |
| estrogen receptor binding, ISS | 1 genes |
| estrogen receptor binding, TAS | 1 genes |
| ER-associated protein catabolism, IDA | 1 genes |
| estrogen receptor signaling pathway, TAS | 1 genes |
| epithelial cell differentiation, NAS | 1 genes |
| exogenous lipid antigen binding, IDA | 1 genes |
| embryonic heart tube development, ISS | 1 genes |
| error-prone postreplication DNA repair, TAS | 1 genes |
| eukaryotic elongation factor-2 kinase activator activity, ISS | 1 genes |
| ErbB-3 class receptor binding, TAS | 1 genes |
| electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity, TAS | 1 genes |
| establishment and/or maintenance of epithelial cell polarity, NAS | 1 genes |
| extracellular polysaccharide biosynthesis, IEA | 1 genes |
| ER retention sequence binding, NAS | 1 genes |
| endosomal lumen acidification, ISS | 1 genes |
AS3D Human
