| oxidoreductase activity, IEA | 363 genes |
| olfactory receptor activity, IEA | 52 genes |
| organogenesis, TAS | 50 genes |
| one-carbon compound metabolism, IEA | 27 genes |
| Original Target List | 26 genes |
| oxygen binding, TAS | 19 genes |
| olfactory receptor activity, NAS | 16 genes |
| OATP, Organic Anion Transporter Polypeptide (OATP) family. This family consists of several eukaryotic Organic-Anion-Transporting Polypeptides (OATPs). Several have been identified mostly in human and rat. Different OATPs vary in tissue distrib | 15 genes |
| outer membrane, IEA | 15 genes |
| oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, IEA | 14 genes |
| OLF, Olfactomedin-like domain | 13 genes |
| OTU, OTU-like cysteine protease. This family is comprised of a group of predicted cysteine proteases, homologous to the Ovarian Tumour (OTU) gene in Drosophila. Members include proteins from eukaryotes, viruses and pathogenic bacterium. The co | 13 genes |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen, IEA | 13 genes |
| Oxysterol_BP, Oxysterol-binding protein | 12 genes |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, IEA | 10 genes |
| ossification, TAS | 9 genes |
| O-linked glycosylation, TAS | 9 genes |
| ossification, IEA | 8 genes |
| Orthopox_C5L, Orthopoxvirus C5L protein. This family consists of several Orthopoxvirus C5L proteins. The function of this family is unknown | 7 genes |
| organic anion transporter activity, TAS | 7 genes |
| OmpH, Outer membrane protein (OmpH-like). This family includes outer membrane proteins such as OmpH among others | 6 genes |
| olfactory receptor activity, TAS | 6 genes |
| oligopeptide transport, IEA | 6 genes |
| organogenesis, NR | 6 genes |
| oxygen transport, IEA | 6 genes |
| organic anion transport, TAS | 6 genes |
| Occludin_ELL, Occludin and RNA polymerase II elongation factor ELL. This family represents a conserved region approximately 100 residues long within eukaryotic occludin proteins and the RNA polymerase II elongation factor ELL. Occludin is an i | 5 genes |
| oxygen transporter activity, IEA | 5 genes |
| outer membrane (sensu Gram-negative Bacteria), IEA | 5 genes |
| organic cation transporter activity, TAS | 5 genes |
| organic anion transport, IEA | 5 genes |
| oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, IEA | 5 genes |
| oxygen binding, NR | 5 genes |
| odontogenesis, NAS | 5 genes |
| Orn_Arg_deC_N, Pyridoxal-dependent decarboxylase, pyridoxal binding domain. These pyridoxal-dependent decarboxylases acting on ornithine, lysine, arginine and related substrates This domain has a TIM barrel fold | 4 genes |
| ORMDL, ORMDL family. Evidence form suggests that ORMDLs are involved in protein folding in the ER | 4 genes |
| ovarian follicle development, NAS | 4 genes |
| oxygen transporter activity, TAS | 4 genes |
| oxidative phosphorylation, TAS | 4 genes |
| oligopeptide transporter activity, IEA | 4 genes |
| oxygen transport, NAS | 4 genes |
| organic cation transport, TAS | 4 genes |
| oxidoreductase activity, acting on NADH or NADPH, IEA | 4 genes |
| Orn_DAP_Arg_deC, Pyridoxal-dependent decarboxylase, C-terminal sheet domain. These pyridoxal-dependent decarboxylases act on ornithine, lysine, arginine and related substrates | 3 genes |
| Osteopontin, Osteopontin | 3 genes |
| Opiods_neuropep, Vertebrate endogenous opioids neuropeptide | 3 genes |
| ODC_AZ, Ornithine decarboxylase antizyme | 3 genes |
| opioid receptor activity, TAS | 3 genes |
| oxygen transporter activity, NAS | 3 genes |
| organelle organization and biogenesis, TAS | 3 genes |
| ornithine decarboxylase inhibitor activity, TAS | 3 genes |
| oxidoreductase activity, NAS | 3 genes |
| oxidoreductase activity, acting on NADH or NADPH, disulfide as acceptor, IEA | 3 genes |
| OTCace, Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain | 2 genes |
| OKR_DC_1, Orn/Lys/Arg decarboxylase, major domain | 2 genes |
| OTCace_N, Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain | 2 genes |
| OGFr_N, Opioid growth factor receptor (OGFr) conserved region. Opioid peptides act as growth factors in neural and non-neural cells and tissues, in addition to serving in neurotransmission/neuromodulation in the nervous system. The Opioid grow | 2 genes |
| OST3_OST6, OST3 / OST6 family. The proteins in this family are part of a complex of eight ER proteins that transfers core oligosaccharide from dolichol carrier to Asn-X-Ser/Thr motifs. This family includes both OST3 and OST6, each of which con | 2 genes |
| OMP_19, Bacterial outer membrane lipoprotein omp19. This family consists of several bacterial outer membrane lipoprotein omp19 sequences | 2 genes |
| OPA3, Optic atrophy 3 protein (OPA3). This family consists of several optic atrophy 3 (OPA3) proteins. OPA3 deficiency causes type III 3-methylglutaconic aciduria (MGA) in humans. This disease manifests with early bilateral optic atrophy, spas | 2 genes |
| OCIA, Ovarian carcinoma immunoreactive antigen (OCIA). This family consists of several ovarian carcinoma immunoreactive antigen (OCIA) and related eukaryotic sequences. The function of this family is unknown | 2 genes |
| opioid peptide activity, IEA | 2 genes |
| oligosaccharyl transferase activity, IEA | 2 genes |
| oligosaccharyl transferase activity, TAS | 2 genes |
| oncostatin-M receptor activity, TAS | 2 genes |
| odorant binding, IEA | 2 genes |
| odorant binding, NAS | 2 genes |
| O-linked glycosylation, IEA | 2 genes |
| oxygen and reactive oxygen species metabolism, NAS | 2 genes |
| oxygen and reactive oxygen species metabolism, TAS | 2 genes |
| oocyte axis determination, TAS | 2 genes |
| opsonization, TAS | 2 genes |
| oligosaccharyl transferase complex, TAS | 2 genes |
| oxysterol 7-alpha-hydroxylase activity, TAS | 2 genes |
| O-sialoglycoprotein endopeptidase activity, IEA | 2 genes |
| oligosaccharide metabolism, ISS | 2 genes |
| oligosaccharide metabolism, TAS | 2 genes |
| oligosaccharide biosynthesis, TAS | 2 genes |
| oxygen transport, TAS | 2 genes |
| orexin receptor activity, IEA | 2 genes |
| oxidoreductase activity, acting on CH-OH group of donors, IEA | 2 genes |
| oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor, IEA | 2 genes |
| ornithine decarboxylase activator activity, ISS | 2 genes |
| Oxidored_molyb, Oxidoreductase molybdopterin binding domain. This domain is found in a variety of oxidoreductases. This domain binds to a molybdopterin cofactor. Xanthine dehydrogenases, that also bind molybdopterin, have essentially no simila | 1 genes |
| OSCP, ATP synthase delta (OSCP) subunit. The ATP D subunit from E. coli is the same as the OSCP subunit which is this family. The ATP D subunit from metazoa are found in family pfam00401 | 1 genes |
| OMPdecase, Orotidine 5'-phosphate decarboxylase / HUMPS family. This family includes Orotidine 5'-phosphate decarboxylase enzymes EC:4.1.1.23 that are involved in the final step of pyrimidine biosynthesis. The family also includes enzymes such | 1 genes |
| Oxidored_q1, NADH-Ubiquinone/plastoquinone (complex I), various chains. This family is part of complex I which catalyses the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across th | 1 genes |
| Oxidored_q6, NADH ubiquinone oxidoreductase, 20 Kd subunit | 1 genes |
| Orexin, Prepro-orexin | 1 genes |
| Ocular_alb, Ocular albinism type 1 protein | 1 genes |
| Oest_recep, Oestrogen receptor | 1 genes |
| OCD_Mu_crystall, Ornithine cyclodeaminase/mu-crystallin family. This family contains the bacterial Ornithine cyclodeaminase enzyme EC:4.3.1.12, which catalyses the deamination of ornithine to proline. This family also contains mu-Crystallin th | 1 genes |
| Octopine_DH_N, NAD/NADP octopine/nopaline dehydrogenase, NAD binding domain. This group of enzymes act on the CH-NH substrate bond using NAD(+) or NADP(+) as an acceptor. The Pfam family consists mainly of octopine and nopaline dehydrogenases | 1 genes |
| OAR, OAR domain | 1 genes |
| Orexin_rec2, Orexin receptor type 2 | 1 genes |
| ORC2, Origin recognition complex subunit 2. All DNA replication initiation is driven by a single conserved eukaryotic initiator complex termed he origin recognition complex (ORC). The ORC is a six protein complex. The function of ORC is review | 1 genes |
| Ocnus, Janus/Ocnus family (Ocnus). This family is comprised of the Ocnus, Janus-A and Janus-B proteins. These proteins have been found to be testes specific in Drosophila melanogaster | 1 genes |
| ORC6, Origin recognition complex subunit 6 (ORC6). This family consists of several eukaryotic origin recognition complex subunit 6 (ORC6) proteins. All DNA replication initiation is driven by a single conserved eukaryotic initiator complex ter | 1 genes |
| Orthopox_A5L, Orthopoxvirus A5L protein. This family consists of several Orthopoxvirus A5L proteins. The vaccinia virus WR A5L open reading frame (corresponding to open reading frame A4L in vaccinia virus Copenhagen) encodes an immunodominant | 1 genes |
| Olfactory_mark, Olfactory marker protein. This family consists of several olfactory marker proteins. Expression of the olfactory marker protein (OMP) is highly restricted to mature olfactory receptor neurons in virtually all vertebrate species | 1 genes |
| ORC3_N, Origin recognition complex (ORC) subunit 3 N-terminus. This family represents the N-terminus (approximately 300 residues) of subunit 3 of the eukaryotic origin recognition complex (ORC). Origin recognition complex (ORC) is composed of | 1 genes |
| Osteoregulin, Osteoregulin. This family represents a conserved region approximately 180 residues long within osteoregulin, a bone-remodelling protein expressed highly in osteocytes within trabecular and cortical bone. A conserved RGD motif is | 1 genes |
| origin of replication recognition complex, IEA | 1 genes |
| ossification, NAS | 1 genes |
| opioid peptide activity, ISS | 1 genes |
| outer dense fiber, NAS | 1 genes |
| oleoyl-[acyl-carrier protein] hydrolase activity, IEA | 1 genes |
| oligo-1,6-glucosidase activity, IEA | 1 genes |
| ornithine carbamoyltransferase activity, NAS | 1 genes |
| ornithine decarboxylase activity, IEA | 1 genes |
| ornithine decarboxylase activity, TAS | 1 genes |
| ornithine-oxo-acid transaminase activity, TAS | 1 genes |
| orotate phosphoribosyltransferase activity, TAS | 1 genes |
| orotidine-5'-phosphate decarboxylase activity, TAS | 1 genes |
| oxoglutarate dehydrogenase (succinyl-transferring) activity, IEA | 1 genes |
| olfactory receptor activity, NR | 1 genes |
| opioid receptor activity, NAS | 1 genes |
| oxytocin receptor activity, TAS | 1 genes |
| oncostatin-M receptor binding, NR | 1 genes |
| oncostatin-M receptor binding, TAS | 1 genes |
| oncostatin-M receptor complex, TAS | 1 genes |
| O-linked glycosylation, ISS | 1 genes |
| O-linked glycosylation, NAS | 1 genes |
| O-linked glycosylation, NR | 1 genes |
| ornithine metabolism, NR | 1 genes |
| one-carbon compound metabolism, NAS | 1 genes |
| oxysterol binding, NAS | 1 genes |
| oxysterol binding, TAS | 1 genes |
| O-methyltransferase activity, IEA | 1 genes |
| O-methyltransferase activity, TAS | 1 genes |
| omega peptidase activity, IDA | 1 genes |
| ornithine cyclodeaminase activity, TAS | 1 genes |
| organic cation porter activity, TAS | 1 genes |
| oligosaccharide metabolism, IDA | 1 genes |
| oligosaccharide metabolism, IEA | 1 genes |
| oligosaccharide metabolism, NAS | 1 genes |
| oligosaccharide biosynthesis, IEA | 1 genes |
| oligosaccharide biosynthesis, ISS | 1 genes |
| ornithine carbamoyltransferase complex, NAS | 1 genes |
| oxoglutarate dehydrogenase complex (sensu Eukarya), NR | 1 genes |
| oxidative photosynthetic carbon pathway, IEA | 1 genes |
| organogenesis, NAS | 1 genes |
| oocyte differentiation, IEP | 1 genes |
| outward rectifier potassium channel activity, NAS | 1 genes |
| oxoglutarate:malate antiporter activity, TAS | 1 genes |
| organic cation transport, IDA | 1 genes |
| organic cation transport, ISS | 1 genes |
| O-glycoside catabolism, NAS | 1 genes |
| O-glycan processing, TAS | 1 genes |
| O-glycan processing, core 3, NAS | 1 genes |
| oxidoreductase activity, IDA | 1 genes |
| oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, IDA | 1 genes |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, IEA | 1 genes |
| oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, IDA | 1 genes |
| oxygen sensor activity, IDA | 1 genes |
| outer membrane, ISS | 1 genes |
| outer membrane, NAS | 1 genes |
| outer membrane, TAS | 1 genes |
| osteoclast differentiation, NAS | 1 genes |
| odontogenesis (sensu Vertebrata), IEA | 1 genes |
| odontogenesis (sensu Vertebrata), ISS | 1 genes |
| odontogenesis, ISS | 1 genes |
| oxoglutarate dehydrogenase complex, IEA | 1 genes |
| organismal physiological process, IEA | 1 genes |