AS3D Human


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Human Gene Lists T
transferase activity, IEA885 genes
transport, IEA381 genes
transcription factor activity, IEA344 genes
transcription factor activity, TAS278 genes
transporter activity, IEA216 genes
Totivirus_coat, Totivirus coat protein181 genes
TolA, TolA protein. This family consists of several bacterial TolA proteins as well as two eukaryotic proteins of unknown function. Tol proteins are involved in the translocation of group A colicins. Colicins are bacterial protein toxins, whic177 genes
transcription from Pol II promoter, TAS136 genes
Target Candidates May 2005 B127 genes
Trypsin, Trypsin124 genes
Tsg101, Tumour susceptibility gene 101 protein (TSG101). This family consists of the eukaryotic tumour susceptibility gene 101 protein (TSG101). Altered transcripts of this gene have been detected in sporadic breast cancers and many other huma114 genes
transferase activity, transferring glycosyl groups, IEA108 genes
transcription factor activity, NAS106 genes
transport, TAS98 genes
trypsin activity, IEA94 genes
transcription coactivator activity, TAS90 genes
TFIIF_alpha, Transcription initiation factor IIF, alpha subunit (TFIIF-alpha). Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) or RNA polymerase II-associating protein 74 (RAP74) is the large subunit of transcription factor II82 genes
transcription corepressor activity, TAS73 genes
transcription factor activity, NR69 genes
transporter activity, TAS62 genes
transcription, IEA56 genes
transmembrane receptor activity, IEA48 genes
TSP_1, Thrombospondin type 1 domain47 genes
Target Candidates Apr.200446 genes
TBC, TBC domain. Identification of a TBC domain in GYP6_YEAST and GYP7_YEAST, which are GTPase activator proteins of yeast Ypt6 and Ypt7, imply that these domains are GTPase activator proteins of Rab-like small GTPases45 genes
transmembrane receptor activity, TAS45 genes
Tektin, Tektin family. Tektins are cytoskeletal proteins. They have been demonstrated in such cellular sites as centrioles, basal bodies, and along ciliary and flagellar doublet microtubules. Tektins form unique protofilaments, organised as lo43 genes
TGF_beta, Transforming growth factor beta like domain37 genes
TAS2R, Mammalian taste receptor protein (TAS2R). This family consists of several forms of mammalian taste receptor proteins (TAS2Rs). TAS2Rs are G protein-coupled receptors expressed in subsets of taste receptor cells of the tongue and palate 37 genes
TT_ORF1, TT viral orf 1. TT virus (TTV), isolated initially from a Japanese patient with hepatitis of unknown aetiology, has since been found to infect both healthy and diseased individuals and numerous prevalence studies have raised questions35 genes
Thioredoxin, Thioredoxin. Thioredoxins are small enzymes that participate in redox reactions, via the reversible oxidation of an active centre disulfide bond. Some members with only the active site are not separated from the noise34 genes
Tropomyosin, Tropomyosin34 genes
TFIIA, Transcription factor IIA, alpha/beta subunit. Transcription initiation factor IIA (TFIIA) is a heterotrimer, the three subunits being known as alpha, beta, and gamma, in order of molecular weight. The N and C-terminal domains of the gam34 genes
Tetraspannin, Tetraspanin family33 genes
translation initiation factor activity, IEA32 genes
transcription from Pol II promoter, NR31 genes
Tubulin, Tubulin/FtsZ family, GTPase domain. This family includes the tubulin alpha, beta and gamma chains, as well as the bacterial FtsZ family of proteins. Members of this family are involved in polymer formation. FtsZ is the polymer-forming30 genes
transcriptional activator activity, NAS30 genes
TIG, IPT/TIG domain. This family consists of a domain that has an immunoglobulin like fold. These domains are found in cell surface receptors such as Met and Ron as well as in intracellular transcription factors where it is involved in DNA bin29 genes
transmembrane receptor protein tyrosine kinase signaling pathway, IEA28 genes
Tubulin_C, Tubulin/FtsZ family, C-terminal domain. This family includes the tubulin alpha, beta and gamma chains, as well as the bacterial FtsZ family of proteins. Members of this family are involved in polymer formation. FtsZ is the polymer-f27 genes
TAFII28, hTAFII28-like protein conserved region. The general transcription factor, TFIID, consists of the TATA-binding protein (TBP) associated with a series of TBP-associated factors (TAFs) that together participate in the assembly of the tra27 genes
tight junction, IEA26 genes
Target Candidates May 2005 A26 genes
TSP_N, Thrombospondin N-terminal -like domain25 genes
Trypan_PARP, Procyclic acidic repetitive protein (PARP). This family consists of several Trypanosoma brucei procyclic acidic repetitive protein (PARP) like sequences. The procyclic acidic repetitive protein (parp) genes of Trypanosoma brucei e25 genes
TGFb_propeptide, TGF-beta propeptide. This propeptide is known as latency associated peptide (LAP) in TGF-beta. LAP is a homodimer which is disulfide linked to TGF-beta binding protein24 genes
transmembrane receptor protein tyrosine kinase signaling pathway, TAS22 genes
TIR, TIR domain. The TIR domain is an intracellular signaling domain found in MyD88, interleukin 1 receptor and the Toll receptor. Called TIR (by SMART?) for Toll - Interleukin - Resistance21 genes
Tropomodulin, Tropomodulin. Tropomodulin is a novel tropomyosin regulatory protein that binds to the end of erythrocyte tropomyosin and blocks head-to-tail association of tropomyosin along actin filaments. Limited proteolysis shows this protei21 genes
Tymo_45kd_70kd, Tymovirus 45/70Kd protein. Tymoviruses are single stranded RNA viruses. This family includes a protein of unknown function that has been named based on its molecular weight. Tymoviruses such as the ononis yellow mosaic tymoviru21 genes
tRNA processing, IEA21 genes
transferase activity, transferring hexosyl groups, IEA20 genes
TraB_pillus, TraB pilus assembly protein. This family consists of several bacterial TraB pilus assembly proteins. TraB is know to be essential for piliation and transfer but very little is known about its specific role in this process. It has 19 genes
tubulin, IEA19 genes
transmembrane receptor protein tyrosine phosphatase activity, TAS18 genes
T-box, T-box. The T-box encodes a 180 amino acid domain that binds to DNA17 genes
transcription factor binding, TAS17 genes
Thyroglobulin_1, Thyroglobulin type-1 repeat. Thyroglobulin type 1 repeats are thought to be involved in the control of proteolytic degradation. The domain usually contains six conserved cysteines. These form three disulphide bridges. Cysteine16 genes
TNF, TNF(Tumour Necrosis Factor) family16 genes
Troponin, Troponin. Troponin (Tn) contains three subunits, Ca2+ binding (TnC), inhibitory (TnI), and tropomyosin binding (TnT). this Pfam contains members of the TnT subunit. Troponin is a complex of three proteins, Ca2+ binding (TnC), inhibit16 genes
tumor necrosis factor receptor binding, IEA16 genes
transporter activity, NR16 genes
tricarboxylic acid cycle, IEA16 genes
transcriptional activator activity, IDA16 genes
TACC, Transforming acidic coiled-coil-containing protein (TACC). This family contains the proteins TACC 1, 2 and 3 the genes for which are found concentrated in the centrosomes of eukaryotic and may play a conserved role in organising centroso15 genes
transcription initiation from Pol II promoter, TAS15 genes
translational initiation, IEA15 genes
transforming growth factor beta receptor signaling pathway, TAS15 genes
TUDOR, Tudor domain. Domain of unknown function present in several RNA-binding proteins. copies in the Drosophila Tudor protein14 genes
transcription cofactor activity, TAS14 genes
transmembrane receptor protein tyrosine kinase activity, TAS14 genes
transaminase activity, IEA14 genes
TPR, TPR Domain13 genes
transcription coactivator activity, NR13 genes
translation initiation factor activity, TAS13 genes
translation elongation factor activity, IEA13 genes
transmembrane receptor activity, NAS13 genes
transcription factor complex, IEA13 genes
transcriptional repressor activity, IDA13 genes
transcriptional repressor activity, NAS13 genes
TTL, Tubulin-tyrosine ligase family. Tubulins and microtubules are subjected to several post-translational modifications of which the reversible detyrosination/tyrosination of the carboxy-terminal end of most alpha-tubulins has been extensivel12 genes
TIP120, TBP (TATA-binding protein) -interacting protein 120 (TIP120). TIP120A is thought to be a unique global transcription factor that can interact with TBP and can stimulate all classes of eukaryotic transcription. TIP120B is specifically e12 genes
transport, NAS12 genes
transport, NR12 genes
transcription regulator activity, IEA12 genes
thyroid hormone receptor binding, IDA12 genes
tRNA-synt_2b, tRNA synthetase class II core domain (G, H, P, S and T). Other tRNA synthetase sub-families are too dissimilar to be included. This domain is the core catalytic domain of tRNA synthetases and includes glycyl, histidyl, prolyl, se11 genes
Transglut_core, Transglutaminase-like superfamily. This family includes animal transglutaminases and other bacterial proteins of unknown function. Sequence conservation in this superfamily primarily involves three motifs that centre around con11 genes
THAP, THAP domain. This THAP domain is a putative DNA-binding domain with a C2CH architecture that probably binds a zinc ion11 genes
two-component signal transduction system (phosphorelay), IEA11 genes
transcription factor TFIID complex, TAS11 genes
transcription, TAS11 genes
transcription initiation, IEA11 genes
translational elongation, IEA11 genes
taste receptor activity, TAS11 genes
ThiF, ThiF family. This family contains a repeated domain in ubiquitin activating enzyme E1 and members of the bacterial ThiF/MoeB/HesA family10 genes
Thi4, Thi4 family. This family includes a putative thiamine biosynthetic enzyme10 genes
Ten_N, Teneurin Intracellular Region. This family is found in the intracellular N-terminal region of the Teneurin family of proteins. These proteins are 'pair-rule' genes and are involved in tissue patterning, specifically probably neural patt10 genes
two-component sensor molecule activity, IEA10 genes
transforming growth factor beta receptor activity, IEA10 genes
transcription, NAS10 genes
transcription initiation from Pol II promoter, IDA10 genes
transcription from Pol III promoter, TAS10 genes
transcriptional activator activity, IEA10 genes
TNFR_c6, TNFR/NGFR cysteine-rich region9 genes
Transglut_N, Transglutaminase family9 genes
Transglut_C, Transglutaminase family, C-terminal ig like domain9 genes
T-cell activation, NAS9 genes
Trefoil, Trefoil (P-type) domain8 genes
tRNA-synt_1, tRNA synthetases class I (I, L, M and V). Other tRNA synthetase sub-families are too dissimilar to be included8 genes
Transket_pyr, Transketolase, pyridine binding domain. This family includes transketolase enzymes, pyruvate dehydrogenases, and branched chain alpha-keto acid decarboxylases8 genes
TFA, Transcription elongation factor A, SII-related family. The function of this family is unclear, but some members are described as transcription elongation factor A, SII-like proteins8 genes
Transformer, Fruit fly transformer protein. This family consists of transformer proteins from several Drosophila species and also from Ceratitis capitata (Mediterranean fruit fly). The transformer locus (tra) produces an RNA processing protein8 genes
transcription factor activity, ISS8 genes
tubulin-tyrosine ligase activity, IEA8 genes
tight junction, TAS8 genes
transcriptional activator activity, TAS8 genes
Thiolase_N, Thiolase, N-terminal domain. Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase7 genes
Tissue_fac, Tissue factor7 genes
TEA, TEA/ATTS domain family7 genes
tRNA_anti, OB-fold nucleic acid binding domain. This family contains OB-fold domains that bind to nucleic acids. The family includes the anti-codon binding domain of lysyl, aspartyl, and asparaginyl -tRNA synthetases (See pfam00152). Aminoacyl7 genes
Thiolase_C, Thiolase, C-terminal domain. Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase7 genes
Triadin, Triadin. This family consists of several eukaryotic triadin proteins. Triadin is a ryanodine receptor and calsequestrin binding protein located in junctional sarcoplasmic reticulum of striated muscles7 genes
tRNA binding, TAS7 genes
transcription coactivator activity, NAS7 genes
transcription factor complex, TAS7 genes
transmembrane receptor protein tyrosine kinase signaling pathway, NAS7 genes
transcriptional activator activity, ISS7 genes
tRNA-synt_2, tRNA synthetases class II (D, K and N). Other tRNA synthetase sub-families are too dissimilar to be included6 genes
TB, TB domain. This domain is also known as the 8 cysteine domain. This family includes the hybrid domains. This cysteine rich repeat is found in TGF binding protein and fibrillin6 genes
Thioesterase, Thioesterase domain. Peptide synthetases are involved in the non-ribosomal synthesis of peptide antibiotics. Next to the operons encoding these enzymes, in almost all cases, are genes that encode proteins that have similarity to 6 genes
TB2_DP1_HVA22, TB2/DP1, HVA22 family. This family includes members from a wide variety of eukaryotes. It includes the TB2/DP1 (deleted in polyposis) protein, which in humans is deleted in severe forms of familial adenomatous polyposis, an auto6 genes
Tctex-1, Tctex-1 family. Tctex-1 is a dynein light chain. It has been shown that Tctex-1 can bind to the cytoplasmic tail of rhodopsin. C-terminal rhodopsin mutations responsible for retinitis pigmentosa inhibit this interaction6 genes
TFR_dimer, Transferrin receptor-like dimerisation domain. This domain is involved in dimerisation of the transferrin receptor as shown in its crystal structure6 genes
TelA, Toxic anion resistance protein (TelA). This family consists of several prokaryotic TelA like proteins. TelA and KlA are associated with tellurite resistance and plasmid fertility inhibition6 genes
Torsin, Torsin. This family consists of several eukaryotic torsin proteins. Torsion dystonia is an autosomal dominant movement disorder characterised by involuntary, repetitive muscle contractions and twisted postures. The most severe early-on6 genes
transcription factor activity, IDA6 genes
transcription cofactor activity, IDA6 genes
translation initiation factor activity, NAS6 genes
transmembrane receptor protein tyrosine kinase activity, IEA6 genes
tRNA ligase activity, IEA6 genes
tumor necrosis factor receptor activity, TAS6 genes
transcription initiation from Pol II promoter, IEA6 genes
telomerase-dependent telomere maintenance, IEA6 genes
telomerase-dependent telomere maintenance, TAS6 genes
transmembrane receptor protein tyrosine phosphatase signaling pathway, TAS6 genes
transcriptional repressor activity, IEA6 genes
transcriptional repressor activity, ISS6 genes
transcriptional repressor activity, TAS6 genes
transferase activity, transferring phosphorus-containing groups, IEA6 genes
transcription initiation factor activity, IEA6 genes
T-cell receptor complex, NAS6 genes
TIM, Triosephosphate isomerase5 genes
tRNA-synt_1b, tRNA synthetases class I (W and Y)5 genes
TCTP, Translationally controlled tumour protein5 genes
TFIIS, Transcription factor S-II (TFIIS)5 genes
Tub, Tub family5 genes
tRNA-synt_2c, tRNA synthetases class II (A). Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only alanyl-tRNA synthetases5 genes
TIL, Trypsin Inhibitor like cysteine rich domain. This family contains trypsin inhibitors as well as a domain found in many extracellular proteins. The domain typically contains ten cysteine residues that form five disulphide bonds. The cystei5 genes
TrkA_N, TrkA-N domain. This domain is found in a wide variety of proteins. These protein include potassium channels, phosphoesterases, and various other transporters. This domain binds to NAD5 genes
Tim17, Tim17/Tim22/Tim23 family. The pre-protein translocase of the mitochondrial outer membrane (Tom) allows the import of pre-proteins from the cytoplasm. Tom forms a complex with a number of proteins, including Tim17. Tim17 and Tim23 are th5 genes
Transketolase_C, Transketolase, C-terminal domain. The C-terminal domain of transketolase has been proposed as a regulatory molecule binding site5 genes
TGS, TGS domain. The TGS domain is named after ThrRS, GTPase, and SpoT. Interestingly, TGS domain was detected also at the amino terminus of the uridine kinase from the spirochaete Treponema pallidum (but not any other organism, including the 5 genes
Transposase_22, L1 transposable element5 genes
TF_AP-2, Transcription factor AP-25 genes
TLE_N, Groucho/TLE N-terminal Q-rich domain. The N-terminal domain of the Grouch/TLE co-repressor proteins are involved in oligomerisation5 genes
TSP_C, Thrombospondin C-terminal region. This region is found at the C-terminus of thrombospondin and related proteins5 genes
triacylglycerol lipase activity, IEA5 genes
transmembrane-ephrin receptor activity, TAS5 genes
traversing start control point of mitotic cell cycle, TAS5 genes
transmembrane receptor protein serine/threonine kinase signaling pathway, TAS5 genes
tRNA processing, TAS5 genes
tetracycline:hydrogen antiporter activity, IEA5 genes
type III site-specific deoxyribonuclease activity, IEA5 genes
tetracycline transport, IEA5 genes
TLV_coat, ENV polyprotein (coat polyprotein)4 genes
Transketolase_N, Transketolase, thiamine diphosphate binding domain. This family includes transketolase enzymes EC:2.2.1.1. and also partially matches to 2-oxoisovalerate dehydrogenase beta subunit EC:1.2.4.4. Both these enzymes utilise thiami4 genes
TIMP, Tissue inhibitor of metalloproteinase. Members of this family are common in extracellular regions of vertebrate species4 genes
TYA, TYA transposon protein. Ty are yeast transposons. A 5.7kb transcript codes for p3 a fusion protein of TYA and TYB. The TYA protein is analogous to the gag protein of retroviruses. TYA a is cleaved to form 46kd protein which can form matur4 genes
TatD_DNase, TatD related DNase. This family of proteins are related to a large superfamily of metalloenzymes. TatD, a member of this family has been shown experimentally to be a DNase enzyme4 genes
TSC22, TSC-22/dip/bun family4 genes
tRNA-synt_1e, tRNA synthetases class I (C) catalytic domain. This family includes only cysteinyl tRNA synthetases4 genes
Thymidylate_kin, Thymidylate kinase4 genes
TBCA, Tubulin binding cofactor A4 genes
tRNA_Me_trans, tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble p4 genes
TMS_TDE, TMS membrane protein/tumour differentially expressed protein (TDE)4 genes
TRAP_alpha, Translocon-associated protein (TRAP), alpha subunit. The alpha-subunit of the TRAP complex (TRAP alpha) is a single-spanning membrane protein of the endoplasmic reticulum (ER) which is found in proximity of nascent polypeptide chai4 genes
TRAPP_Bet3, Transport protein particle (TRAPP) component, Bet3. TRAPP plays a key role in the targeting and/or fusion of ER-to-Golgi transport vesicles with their acceptor compartment. TRAPP is an 800 KDa that contains at least 10 subunits4 genes
Tht1, Tht1-like nuclear fusion protein4 genes
TPD52, Tumour protein D52 family. The hD52 gene was originally identified through its elevated expression level in human breast carcinoma. Cloning of D52 homologues from other species has indicated that D52 may play roles in calcium-mediated s4 genes
Tweety, Tweety. The tweety (tty) gene has not been characterised at the protein level. However, it is thought to form a membrane protein with five potential membrane-spanning regions. A number of potential functions have been suggested in4 genes
translation release factor activity, IEA4 genes
triacylglycerol lipase activity, TAS4 genes
thyroid hormone receptor activity, TAS4 genes
thromboxane receptor activity, IEA4 genes
transmembrane receptor protein tyrosine kinase adaptor protein activity, TAS4 genes
transporter activity, NAS4 genes
telomerase holoenzyme complex, IDA4 genes
transcription from Pol I promoter, TAS4 genes
tRNA splicing, IEA4 genes
translational elongation, NAS4 genes
translational elongation, TAS4 genes
translational termination, IEA4 genes
tRNA aminoacylation for protein translation, IEA4 genes
tachykinin signaling pathway, TAS4 genes
tRNA processing, NAS4 genes
transcription factor binding, IPI4 genes
transcription factor binding, ISS4 genes
translation factor activity, nucleic acid binding, TAS4 genes
thiol-disulfide exchange intermediate activity, TAS4 genes
transcription regulator activity, NAS4 genes
T-cell activation, TAS4 genes
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity, IEA4 genes
Tyrosinase, Common central domain of tyrosinase. This family also contains polyphenol oxidases and some hemocyanins. Binds two copper ions via two sets of three histidines. This family is related to pfam003723 genes
TBP, Transcription factor TFIID (or TATA-binding protein, TBP)3 genes
Transferrin, Transferrin3 genes
Tubulin-binding, Tau and MAP protein, tubulin-binding repeat3 genes
THF_DHG_CYH, Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain3 genes
T4_deiodinase, Iodothyronine deiodinase3 genes
TruB_N, TruB family pseudouridylate synthase (N terminal domain). Members of this family are involved in modifying bases in RNA molecules. They carry out the conversion of uracil bases to pseudouridine. This family includes TruB, a pseudouridy3 genes
THF_DHG_CYH_C, Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain3 genes
THUMP, THUMP domain. The THUMP domain is named after after thiouridine synthases, methylases and PSUSs. The THUMP domain consists of about 110 amino acid residues. It is predicted that this domain is an RNA-binding domain that adopts an alpha/3 genes
Treacle, Treacher Collins syndrome protein Treacle3 genes
tRNA_m1G_MT_9, tRNA m(1)G methyltransferase. Family member HYNA is the product of a novel gene expressed in human liver cancer tissue. This methyltransferase is responsible for methylation of tRNA at the N-1 position of guanosine to form m(1)G3 genes
TIMELESS_C, Timeless protein C terminal region. The timeless (tim) gene is essential for circadian function in Drosophila. Putative homologues of Drosophila tim have been identified in both mice and humans (mTim and hTIM, respectively). Mammal3 genes
TM2, TM2 domain. This family is composed of a pair of transmembrane alpha helices connected by a short linker. The function of this domain is unknown, however it occurs in a wide range or protein contexts3 genes
tRNA-synt_1d_C, DALR anticodon binding domain. This all alpha helical domain is the anticodon binding domain in Arginyl and glycyl tRNA synthetase. This domain is known as the DALR domain after characteristic conserved amino acids3 genes
Tcp11, T-complex protein 11. This family consists of several eukaryotic T-complex protein 11 (Tcp11) related sequences. Tcp11 is only expressed in fertile adult mammalian testes and is thought to be important in sperm function and fertility. T3 genes
Tcp10_C, T-complex protein 10 C-terminus. This family represents the C-terminus (approximately 180 residues) of eukaryotic T-complex protein 10. The T-complex is involved in spermatogenesis in mice3 genes
tRNA binding, IEA3 genes
tRNA-intron endonuclease activity, IEA3 genes
tRNA-intron endonuclease complex, IEA3 genes
transcription corepressor activity, NAS3 genes
transcription corepressor activity, NR3 genes
telomerase activity, IDA3 genes
translation elongation factor activity, NAS3 genes
threonine-tRNA ligase activity, IEA3 genes
type 1 serine/threonine specific protein phosphatase inhibitor activity, TAS3 genes
transmembrane receptor activity, ISS3 genes
tachykinin receptor activity, TAS3 genes
tropomyosin binding, IEA3 genes
tropomyosin binding, TAS3 genes
transcription factor TFIID complex, IEA3 genes
transcription factor TFIIH complex, TAS3 genes
troponin complex, NR3 genes
tight junction, ISS3 genes
tight junction, NR3 genes
tricarboxylic acid cycle, NR3 genes
transcription-coupled nucleotide-excision repair, IDA3 genes
transcription, DNA-dependent, NAS3 genes
translational initiation, NAS3 genes
translational initiation, TAS3 genes
threonyl-tRNA aminoacylation, IEA3 genes
telomerase-dependent telomere maintenance, NAS3 genes
transmembrane receptor protein serine/threonine kinase signaling pathway, IEA3 genes
transforming growth factor beta receptor complex assembly, TAS3 genes
tyrosine phosphorylation of STAT protein, TAS3 genes
transcription elongation factor complex, TAS3 genes
thrombin receptor activity, TAS3 genes
transmembrane receptor protein tyrosine kinase activator activity, NAS3 genes
T-helper 2 type immune response, TAS3 genes
T-cell activation, ISS3 genes
telomeric DNA binding, TAS3 genes
thyroid hormone receptor binding, NAS3 genes
thyroid hormone receptor binding, TAS3 genes
TPP_enzyme_M, Thiamine pyrophosphate enzyme, central domain. The central domain of TPP enzymes contains a 2-fold Rossman fold2 genes
TFIIB, Transcription factor TFIIB repeat2 genes
Transthyretin, Transthyretin precursor (formerly prealbumin). Transthyretin is a thyroid hormone-binding protein that transports thyroxine from the bloodstream to the brain. Mutations in the human transthyretin are associated with several gene2 genes
tRNA-synt_1c, tRNA synthetases class I (E and Q), catalytic domain. Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only glutamyl and glutaminyl tRNA synthetases. In some organisms, a single glutamyl-2 genes
tRNA-synt_1d, tRNA synthetases class I (R). Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only arginyl tRNA synthetase2 genes
Topoisom_I, Eukaryotic DNA topoisomerase I, catalytic core. Topoisomerase I promotes the relaxation of DNA superhelical tension by introducing a transient single-stranded break in duplex DNA and are vital for the processes of replication, tran2 genes
Topoisom_bac, DNA topoisomerase. This subfamily of topoisomerase is divided on the basis that these enzymes preferentially relax negatively supercoiled DNA, from a 5' phospho- tyrosine linkage in the enzyme-DNA covalent intermediate and has hi2 genes
tRNA-synt_2d, tRNA synthetases class II core domain (F). Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only phenylalanyl-tRNA synthetases. This is the core catalytic domain2 genes
tRNA_bind, Putative tRNA binding domain. This domain is found in prokaryotic methionyl-tRNA synthetases, prokaryotic phenylalanyl tRNA synthetases the yeast GU4 nucleic-binding protein (G4p1 or p42, ARC1), human tyrosyl-tRNA synthetase, and en2 genes
Transposase_12, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS11652 genes
TGT, Queuine tRNA-ribosyltransferase. This is a family of queuine tRNA-ribosyltransferases EC:2.4.2.29, also known as tRNA-guanine transglycosylase and guanine insertion enzyme. Queuine tRNA-ribosyltransferase modifies tRNAs for asparagine, as2 genes
TCL1_MTCP1, TCL1/MTCP1 family. Two related oncogenes, TCL-1 and MTCP-1, are overexpressed in T cell prolymphocytic leukaemias as a result of chromosomal rearrangements that involve the translocation of one T cell receptor gene to either chromo2 genes
tRNA_int_endo, tRNA intron endonuclease, catalytic C-terminal domain. Members of this family cleave pre tRNA at the 5' and 3' splice sites to release the intron EC:3.1.27.92 genes
Translin, Translin family. Members of this family include Translin, which interacts with DNA and forms a ring around the DNA. This family also includes, which was found to interact with translin with yeast two-hybrid screen2 genes
TRM, N2,N2-dimethylguanosine tRNA methyltransferase. This enzyme EC:2.1.1.32 used S-AdoMet to methylate tRNA. The TRM1 gene of Saccharomyces cerevisiae is necessary for the N2,N2-dimethylguanosine modification of both mitochondrial and cytopla2 genes
TFIID-31kDa, Transcription initiation factor IID, 31kD subunit. This family represents the N-terminus of the 31kD subunit (42kD in drosophila) of transcription initiation factor IID (TAFII31). TAFII31 binds to p53, and is an essential requirem2 genes
Tyr_Deacylase, D-Tyr-tRNA(Tyr) deacylase. This family comprises of several D-Tyr-tRNA(Tyr) deacylase proteins. Cell growth inhibition by several d-amino acids can be explained by an in vivo production of d-aminoacyl-tRNA molecules. Escherichia2 genes
TPP_enzyme_N, Thiamine pyrophosphate enzyme, N-terminal TPP binding domain2 genes
Topoisom_I_N, Eukaryotic DNA topoisomerase I, DNA binding fragment. Topoisomerase I promotes the relaxation of DNA superhelical tension by introducing a transient single-stranded break in duplex DNA and are vital for the processes of replicati2 genes
TAF, TATA box binding protein associated factor (TAF). TAF proteins adopt a histone-like fold2 genes
TspO_MBR, TspO/MBR family. Tryptophan-rich sensory protein (TspO) is an integral membrane protein that acts as a negative regulator of the expression of specific photosynthesis genes in response to oxygen/light. It is involved in the efflux of2 genes
Trp_Tyr_perm, Tryptophan/tyrosine permease family2 genes
TSA, Type specific antigen. There are several antigenic variants in Rickettsia tsutsugamushi, and a type-specific antigen (TSA) of 56-kilodaltons located on the rickettsial surface is responsible for the variation. TSA proteins are probably in2 genes
TF_Otx, Otx1 transcription factor2 genes
TAP_C, TAP C-terminal domain. The vertebrate Tap protein is a member of the NXF family of shuttling transport receptors for nuclear export of mRNA. Tap has a modular structure, and its most C-terminal domain is important for binding to FG repe2 genes
tRNA-synt_1c_C, tRNA synthetases class I (E and Q), anti-codon binding domain. Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only glutamyl and glutaminyl tRNA synthetases. In some organisms, a singl2 genes
Tim44, Tim44-like domain. Tim44 is an essential component of the machinery that mediates the translocation of nuclear-encoded proteins across the mitochondrial inner membrane. Tim44 is thought to bind phospholipids of the mitochondrial inner m2 genes
Tom22, Mitochondrial import receptor subunit Tom22. The mitochondrial protein translocase family, which is responsible for movement of nuclear encoded preproteins into mitochondria, is very complex with at least 19 components. These proteins i2 genes
TFIID_90kDa, WD40 associated region in TFIID subunit. This region, possibly a domain is found in subunits of transcription factor TFIID. The function of this region is unknown2 genes
Tis11B_C, Tis11B like protein, C terminus. Members of this family always contain a tandem repeat of CCCH zinc fingers pfam00642. Tis11B, Tis11D and their homologues are thought to be regulatory proteins involved in the response to growth facto2 genes
TAFII55_N, TAFII55 protein conserved region. The general transcription factor, TFIID, consists of the TATA-binding protein (TBP) associated with a series of TBP-associated factors (TAFs) that together participate in the assembly of the transcr2 genes
TAF4, Transcription initiation factor TFIID component TAF4 family. This region of similarity is found in Transcription initiation factor TFIID component TAF42 genes
TMEM9, TMEM9. This family contains several eukaryotic transmembrane proteins which are homologous to human transmembrane protein 9. The TMEM9 gene encodes a 183 amino-acid protein that contains an N-terminal signal peptide, a single transmembr2 genes
Trigger_C, Bacterial trigger factor protein (TF) C-terminus. In the E. coli cytosol, a fraction of the newly synthesised proteins requires the activity of molecular chaperones for folding to the native state. The major chaperones implicated in2 genes
TPMT, Thiopurine S-methyltransferase (TPMT). This family consists of thiopurine S-methyltransferase proteins from both eukaryotes and prokaryotes. Thiopurine S-methyltransferase (TPMT) is a cytosolic enzyme that catalyses S-methylation of arom2 genes
TROVE, TROVE domain. This presumed domain is found in TEP1 and Ro60 proteins, that are RNA-binding components of Telomerase, Ro and Vault RNPs. This domain has been named TROVE, (after Telomerase, Ro and Vault). This domain is probably RNA-bin2 genes
tRNA_U5-meth_tr, tRNA (Uracil-5-)-methyltransferase. This family consists of (Uracil-5-)-methyltransferases EC:2.1.1.35 from bacteria, archaea and eukaryotes. A 5-methyluridine (m(5)U) residue at position 54 is a conserved feature of bacterial2 genes
TIP49, TIP49 C-terminus. This family consists of the C-terminal region of several eukaryotic and archaeal RuvB-like 1 (Pontin or TIP49a) and RuvB-like 2 (Reptin or TIP49b) proteins. The N-terminal domain contains the pfam00004 domain. In zebra2 genes
TRAP_240kDa, TRAP240. Members of this family have been shown to be involved in transcriptional repression via the Mediator complex2 genes
TRI12, Fungal trichothecene efflux pump (TRI12). This family consists of several fungal specific trichothecene efflux pump proteins. Many of the genes involved in trichothecene toxin biosynthesis in Fusarium sporotrichioides are present within2 genes
transcription factor TFIIIC complex, TAS2 genes
transcriptional elongation regulator activity, NR2 genes
transcriptional elongation regulator activity, TAS2 genes
transcription cofactor activity, IEA2 genes
transcription cofactor activity, NR2 genes
transcription coactivator activity, IDA2 genes
transcription corepressor activity, ISS2 genes
thrombin activity, IEA2 genes
tissue kallikrein activity, NAS2 genes
tissue kallikrein activity, TAS2 genes
trypsin activity, TAS2 genes
thioredoxin-disulfide reductase activity, ISS2 genes
thiosulfate sulfurtransferase activity, TAS2 genes
thymidine kinase activity, TAS2 genes
transketolase activity, TAS2 genes
transposase activity, TAS2 genes
tRNA (guanine-N2-)-methyltransferase activity, IEA2 genes
tryptophan-tRNA ligase activity, IEA2 genes
thyroid-stimulating hormone receptor activity, TAS2 genes
transferrin receptor activity, NAS2 genes
tumor necrosis factor receptor activity, NAS2 genes
Toll binding, NAS2 genes
transforming growth factor beta receptor binding, IEA2 genes
transforming growth factor beta receptor binding, NR2 genes
transforming growth factor beta receptor binding, TAS2 genes
tumor necrosis factor receptor binding, NAS2 genes
tropomyosin binding, NAS2 genes
tropomyosin binding, NR2 genes
transcription factor complex, ISS2 genes
transcription factor TFIIE complex, NR2 genes
transcription factor TFIIH complex, NAS2 genes
tight junction, IDA2 genes
tricarboxylic acid cycle, TAS2 genes
thioredoxin pathway, NAS2 genes
transcription, IDA2 genes
transcription, DNA-dependent, TAS2 genes
transcription initiation from Pol II promoter, ISS2 genes
transcription from Pol III promoter, NR2 genes
transcription initiation from Pol III promoter, TAS2 genes
tryptophanyl-tRNA aminoacylation, IEA2 genes
tyrosine catabolism, TAS2 genes
thyroid hormone generation, IEA2 genes
thyroid hormone generation, TAS2 genes
triacylglycerol metabolism, TAS2 genes
tetrahydrobiopterin biosynthesis, IEA2 genes
thiamin metabolism, TAS2 genes
transmembrane receptor protein tyrosine kinase ligand binding, NAS2 genes
transmembrane receptor protein tyrosine kinase activation (dimerization), ISS2 genes
transforming growth factor beta receptor signaling pathway, NAS2 genes
transforming growth factor beta receptor signaling pathway, NR2 genes
thioredoxin peroxidase activity, TAS2 genes
thrombin receptor activity, IEA2 genes
tubulin binding, ISS2 genes
tubulin binding, TAS2 genes
transcription initiation factor activity, NAS2 genes
transmission of nerve impulse, IEP2 genes
tryptase activity, IEA2 genes
transport vesicle, TAS2 genes
T-cell differentiation, NAS2 genes
transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity, TAS2 genes
T-cell activation, IC2 genes
T-cell receptor binding, NAS2 genes
tubulin, ISS2 genes
tubulin, NAS2 genes
TRAIL binding, NAS2 genes
TK, Thymidine kinase1 genes
Thymidylat_synt, Thymidylate synthase1 genes
TP_methylase, Tetrapyrrole (Corrin/Porphyrin) Methylases. This family uses S-AdoMet in the methylation of diverse substrates. This family includes a related group of bacterial proteins of unknown function. This family includes the methylase Di1 genes
Transaldolase, Transaldolase1 genes
TruD, tRNA pseudouridine synthase D (TruD). TruD is responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs1 genes
Trehalase, Trehalase1 genes
TP2, Nuclear transition protein 21 genes
Transposase_1, Transposase. This family includes the mariner transposase1 genes
Toprim, Toprim domain. This is a conserved region from DNA primase. This corresponds to the Toprim domain common to DnaG primases, topoisomerases, OLD family nucleases and RecR proteins. Both DnaG motifs IV and V are present in the alignment, 1 genes
TRAM, TRAM domain. This small domain has no known function. However it may perform a nucleic acid binding role1 genes
TraB, TraB family. pAD1 is a hemolysin/bacteriocin plasmid originally identified in Enterococcus faecalis DS16. It encodes a mating response to a peptide sex pheromone, cAD1, secreted by recipient bacteria. Once the plasmid pAD1 is acquired, p1 genes
TFIIE_alpha, TFIIE alpha subunit. The general transcription factor TFIIE has an essential role in eukaryotic transcription initiation together with RNA polymerase II and other general factors. Human TFIIE consists of two subunits, TFIIE-alpha 1 genes
TFIIE_beta, TFIIE beta subunit core domain. General transcription factor TFIIE consists of two subunits, TFIIE alpha pfam02002 and TFIIE beta. TFIIE beta has been found to bind to the region where the promoter starts to open to be single-stran1 genes
TFIIA_gamma_N, Transcription initiation factor IIA, gamma subunit, helical domain. Accurate transcription in vivo requires at least six general transcription initiation factors, in addition to RNA polymerase II. Transcription initiation factor1 genes
TFIID-18kDa, Transcription initiation factor IID, 18kD subunit. This family includes the Spt3 yeast transcription factors and the 18kD subunit from human transcription initiation factor IID (TFIID-18). Determination of the crystal structure re1 genes
TFIIF_beta, Transcription initiation factor IIF, beta subunit. Accurate transcription in vivo requires at least six general transcription initiation factors, in addition to RNA polymerase II. Transcription initiation factor IIF (TFIIF) is a te1 genes
Telo_bind_N, Telomere-binding protein alpha subunit, N-terminal domain. The telomere-binding protein forms a heterodimer in ciliates consisting of an alpha and a beta subunit. This complex may function as a protective cap for the single-strand1 genes
TIL_assoc, TILa domain. This cysteine rich domain occurs along side the TIL pfam01826 domain and is likely to be a distantly related relative. This domain is found five to twenty-five times in zonadhesins. The TILa domain is also found twice i1 genes
ThiI, Thiamine biosynthesis protein (ThiI). ThiI is required for thiazole synthesis, required for thiamine biosynthesis1 genes
ThiS, ThiS family. ThiS (thiaminS) is a 66 aa protein involved in sulphur transfer. ThiS is coded in the thiCEFSGH operon in E. coli. This family of proteins have two conserved Glycines at the COOH terminus. Thiocarboxylate is formed at the la1 genes
TFIIA_gamma_C, Transcription initiation factor IIA, gamma subunit, beta-barrel domain. Accurate transcription in vivo requires at least six general transcription initiation factors, in addition to RNA polymerase II. Transcription initiation fa1 genes
Trp_dioxygenase, Tryptophan 2,3-dioxygenase1 genes
TATR, Trans-activating transcriptional regulator. This family of trans-activating transcriptional regulator (TATR), also known as intermediate early protein 1, are common to the Nucleopolyhedroviruses1 genes
TFIID_30kDa, Transcription initiation factor TFIID 23-30kDa subunit1 genes
Tuberin, Tuberin. Tuberous sclerosis complex (TSC) is an autosomal dominant disorder and is characterized by the presence of hamartomas in many organs, such as brain, skin, heart, lung, and kidney. It is caused by mutation either TSC1 or TSC2 1 genes
TFIID_20kDa, Transcription initiation factor TFIID subunit A1 genes
Tfb2, Transcription factor Tfb21 genes
Tfb4, Transcription factor Tfb41 genes
TPR_div1, TPR repeat region. This family represents a set of three divergent TPR repeats found in a small group of uncharacterised proteins1 genes
TIP41, TIP41-like family. The TOR signalling pathway activates a cell-growth program in response to nutrients. TIP41 interacts with TAP42 and negatively regulates the TOR signaling pathway1 genes
TAP42, TAP42-like family. The TOR signalling pathway activates a cell-growth program in response to nutrients. TIP41 (pfam04176) interacts with TAP42 and negatively regulates the TOR signaling pathway1 genes
TPK_catalytic, Thiamin pyrophosphokinase, catalytic domain. Family of thiamin pyrophosphokinase (EC:2.7.6.2). Thiamin pyrophosphokinase (TPK) catalyses the transfer of a pyrophosphate group from ATP to vitamin B1 (thiamin) to form the coenzyme1 genes
TPK_B1_binding, Thiamin pyrophosphokinase, vitamin B1 binding domain. Family of thiamin pyrophosphokinase (EC:2.7.6.2). Thiamin pyrophosphokinase (TPK) catalyses the transfer of a pyrophosphate group from ATP to vitamin B1 (thiamin) to form th1 genes
TP6A_N, Type IIB DNA topoisomerase. Type II DNA topoisomerases are ubiquitous enzymes that catalyse the ATP-dependent transport of one DNA duplex through a second DNA segment via a transient double-strand break. Type II DNA topoisomerases are 1 genes
tRNA_synt_1c_R2, Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2. This is a region found N terminal to the catalytic domain of glutaminyl-tRNA synthetase (EC 6.1.1.18) in eukaryotes but not in Escherichia coli. This region i1 genes
tRNA_synt_1c_R1, Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1. This is a region found N terminal to the catalytic domain of glutaminyl-tRNA synthetase (EC 6.1.1.18) in eukaryotes but not in Escherichia coli. This region i1 genes
Tsg, Twisted gastrulation (Tsg) protein conserved region. Tsg was identified in Drosophila as being required to specify the dorsal-most structures in the embryo, for example amnioserosa. Biochemical experiments have revealed three key properti1 genes
Transposase_30, Bacillus transposase protein. This family of putative transposases includes mostly Bacillus members. However, we have also found a Bacillus subtilis bacteriophage SPbetac2 homologue, possibly arising as a result of horizontal t1 genes
TIMELESS, Timeless protein. The timeless gene in Drosophila melanogaster and its homologues in a number of other insects and mammals (including human) are involved in circadian rhythm control. This family includes a related proteins from a num1 genes
TH1, TH1 protein. TH1 is a highly conserved but uncharacterised metazoan protein. No homologue has been identified in Caenorhabditis elegans. TH1 binds specifically to A-Raf kinase1 genes
TEP1_N, TEP1 N-terminal domain. This short sequence region is found in four copies at the N-terminus of the TEP1 telomerase component. The functional significance of the region is uncertain. However the conservation of two histidines and a cys1 genes
TRAP-delta, Translocon-associated protein, delta subunit precursor (TRAP-delta). This family consists of several eukaryotic translocon-associated protein, delta subunit precursors (TRAP-delta or SSR-delta). The exact function of this protein i1 genes
TRH, Thyrotropin-releasing hormone (TRH). This family consists of several thyrotropin-releasing hormone (TRH) proteins. Thyrotropin-Releasing Hormone (TRH; pyroGlu-His-Pro-NH2), originally isolated as a hypothalamic neuropeptide hormone, most 1 genes
TRAP_beta, Translocon-associated protein beta (TRAPB). This family consists of several eukaryotic translocon-associated protein beta (TRAPB) or signal sequence receptor beta subunit (SSR-beta) proteins. The normal translocation of nascent poly1 genes
Tyr-DNA_phospho, Tyrosyl-DNA phosphodiesterase. Covalent intermediates between topoisomerase I and DNA can become dead-end complexes that lead to cell death. Tyrosyl-DNA phosphodiesterase can hydrolyse the bond between topoisomerase I and DNA1 genes
TPX2, Targeting protein for Xklp2 (TPX2). This family represents a conserved region approximately 60 residues long within the eukaryotic targeting protein for Xklp2 (TPX2). Xklp2 is a kinesin-like protein localised on centrosomes throughout th1 genes
TRAP-gamma, Translocon-associated protein, gamma subunit (TRAP-gamma). This family consists of several eukaryotic translocon-associated protein, gamma subunit (TRAP-gamma) sequences. The translocation site (translocon), at which nascent polype1 genes
TBPIP, Tat binding protein 1(TBP-1)-interacting protein (TBPIP). This family consists of several eukaryotic TBP-1 interacting protein (TBPIP) sequences. TBP-1 has been demonstrated to interact with the human immunodeficiency virus type 1 (HIV-1 genes
tRNA binding, IDA1 genes
tRNA binding, ISS1 genes
tRNA binding, NAS1 genes
transcription factor TFIIIB complex, NAS1 genes
two-component signal transduction system (phosphorelay), NAS1 genes
telomere maintenance, TAS1 genes
translation repressor activity, nucleic acid binding, ISS1 genes
translation repressor activity, nucleic acid binding, NAS1 genes
thermoregulation, ISS1 genes
transcription factor activity, IMP1 genes
transcriptional elongation regulator activity, IEA1 genes
transcriptional elongation regulator activity, NAS1 genes
transcription cofactor activity, IPI1 genes
transcription cofactor activity, ISS1 genes
transcription coactivator activity, IEA1 genes
transcription coactivator activity, IMP1 genes
transcription corepressor activity, IDA1 genes
transcription termination factor activity, NAS1 genes
transcription termination factor activity, TAS1 genes
telomeric template RNA reverse transcriptase activity, IEA1 genes
telomeric template RNA reverse transcriptase activity, TAS1 genes
translation initiation factor activity, IDA1 genes
translation initiation factor activity, ISS1 genes
translation elongation factor activity, NR1 genes
translation elongation factor activity, TAS1 genes
translation release factor activity, TAS1 genes
thrombin activity, IDA1 genes
tripeptidyl-peptidase II activity, TAS1 genes
trypsin activity, NAS1 genes
tetrahydrofolylpolyglutamate synthase activity, TAS1 genes
tryptophan 5-monooxygenase activity, IEA1 genes
tyrosine 3-monooxygenase activity, IEA1 genes
tyrosine 3-monooxygenase activity, TAS1 genes
transmembrane receptor protein tyrosine kinase activity, IDA1 genes
transmembrane receptor protein tyrosine kinase activity, NAS1 genes
thiamin diphosphokinase activity, IEA1 genes
thioredoxin-disulfide reductase activity, IDA1 genes
thioredoxin-disulfide reductase activity, NAS1 genes
thioredoxin-disulfide reductase activity, TAS1 genes
threonine synthase activity, IEA1 genes
thromboxane-A synthase activity, IEA1 genes
thymidylate kinase activity, TAS1 genes
thymidylate synthase activity, IEA1 genes
thyroxine 5'-deiodinase activity, IEA1 genes
thyroxine 5'-deiodinase activity, NAS1 genes
thyroxine 5'-deiodinase activity, TAS1 genes
transaldolase activity, IEA1 genes
transaldolase activity, TAS1 genes
triacylglycerol lipase activity, NAS1 genes
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity, NAS1 genes
tRNA adenylyltransferase activity, IDA1 genes
tRNA isopentenyltransferase activity, TAS1 genes
tryptophan-tRNA ligase activity, NR1 genes
tyrosine-tRNA ligase activity, IEA1 genes
tyrosine-tRNA ligase activity, TAS1 genes
tryptophan 2,3-dioxygenase activity, TAS1 genes
tyrosine transaminase activity, NAS1 genes
type 1 serine/threonine specific protein phosphatase inhibitor activity, NR1 genes
thyroid hormone receptor activity, IEA1 genes
transmembrane receptor activity, IC1 genes
transmembrane receptor activity, IMP1 genes
transmembrane receptor activity, NR1 genes
thromboxane A2 receptor activity, TAS1 genes
tachykinin receptor activity, IEA1 genes
thyrotropin-releasing hormone receptor activity, TAS1 genes
transmembrane receptor protein tyrosine phosphatase activity, ISS1 genes
transforming growth factor beta receptor activity, NAS1 genes
type I transforming growth factor beta receptor activity, TAS1 genes
type II transforming growth factor beta receptor activity, TAS1 genes
transmembrane receptor protein tyrosine kinase signaling protein activity, TAS1 genes
transmembrane receptor protein tyrosine kinase adaptor protein activity, NR1 genes
transmembrane receptor protein tyrosine kinase docking protein activity, TAS1 genes
transforming growth factor beta receptor, cytoplasmic mediator activity, NR1 genes
transforming growth factor beta receptor, cytoplasmic mediator activity, TAS1 genes
tumor necrosis factor receptor binding, IPI1 genes
tumor necrosis factor receptor binding, TAS1 genes
transporter activity, IDA1 genes
transporter activity, ISS1 genes
taurine:sodium symporter activity, TAS1 genes
t-SNARE activity, NR1 genes
t-SNARE activity, TAS1 genes
transcription factor complex, IDA1 genes
transcription factor complex, IPI1 genes
transcription factor complex, NAS1 genes
transcription factor TFIID complex, NR1 genes
transcription factor TFIIA complex, NAS1 genes
transcription factor TFIIA complex, NR1 genes
transcription factor TFIIE complex, TAS1 genes
transcription factor TFIIF complex, NR1 genes
transcription factor TFIIF complex, TAS1 genes
translocon, NAS1 genes
troponin complex, NAS1 genes
troponin complex, TAS1 genes
tight junction, NAS1 genes
trehalose catabolism, TAS1 genes
thioredoxin pathway, ISS1 genes
thymidine catabolism, NAS1 genes
transcription-coupled nucleotide-excision repair, NR1 genes
transcription-coupled nucleotide-excision repair, TAS1 genes
transcription, NR1 genes
transcription, DNA-dependent, NR1 genes
transcription initiation, NAS1 genes
transcription initiation, NR1 genes
transcription termination, IEA1 genes
transcription termination, NAS1 genes
transcription termination, TAS1 genes
transcription from Pol II promoter, IDA1 genes
transcription from Pol II promoter, IEA1 genes
transcription from Pol II promoter, IMP1 genes
transcription from Pol II promoter, ISS1 genes
transcription from Pol II promoter, NAS1 genes
transcription termination from Pol II promoter, TAS1 genes
transcription from Pol III promoter, IDA1 genes
transcription from mitochondrial promoter, TAS1 genes
tRNA metabolism, IEA1 genes
tRNA modification, IDA1 genes
tRNA modification, IEA1 genes
tRNA modification, TAS1 genes
tRNA-nucleus export, IEA1 genes
tRNA aminoacylation for protein translation, TAS1 genes
tryptophanyl-tRNA aminoacylation, TAS1 genes
tyrosyl-tRNA aminoacylation, IEA1 genes
tyrosyl-tRNA aminoacylation, TAS1 genes
tryptophan metabolism, IEA1 genes
tryptophan catabolism, NR1 genes
tryptophan catabolism, TAS1 genes
tyrosine metabolism, IEA1 genes
tyrosine catabolism, IEA1 genes
tyrosine catabolism, NAS1 genes
thyroid hormone generation, NR1 genes
triacylglycerol metabolism, IC1 genes
triacylglycerol metabolism, ISS1 genes
triacylglycerol metabolism, NAS1 genes
triacylglycerol metabolism, NR1 genes
tetrahydrobiopterin biosynthesis, TAS1 genes
thiamin metabolism, IEA1 genes
transport, ISS1 genes
tubulin folding, TAS1 genes
traversing start control point of mitotic cell cycle, NR1 genes
transmembrane receptor protein tyrosine kinase signaling pathway, IDA1 genes
transmembrane receptor protein tyrosine kinase ligand binding, TAS1 genes
transmembrane receptor protein tyrosine kinase activation (dimerization), IDA1 genes
transmembrane receptor protein tyrosine kinase activation (dimerization), NAS1 genes
transmembrane receptor protein tyrosine kinase activation (dimerization), TAS1 genes
transmembrane receptor protein serine/threonine kinase signaling pathway, ISS1 genes
transmembrane receptor protein serine/threonine kinase signaling pathway, NAS1 genes
tachykinin signaling pathway, IEA1 genes
transcription elongation factor complex, IPI1 genes
transcription elongation factor complex, NAS1 genes
thiopurine S-methyltransferase activity, TAS1 genes
transcription factor binding, IDA1 genes
transcription factor binding, NAS1 genes
transcription factor binding, NR1 genes
translation factor activity, nucleic acid binding, NAS1 genes
tRNA (guanine-N7-)-methyltransferase activity, IDA1 genes
tRNA guanylyltransferase activity, TAS1 genes
tRNA specific adenosine deaminase activity, TAS1 genes
tocopherol binding, NAS1 genes
tocopherol binding, TAS1 genes
thyrotropin-releasing hormone activity, TAS1 genes
tetracycline transporter activity, TAS1 genes
translation activator activity, NR1 genes
thymidine phosphorylase activity, TAS1 genes
threonine biosynthesis, IEA1 genes
thiamin diphosphate biosynthesis, IEA1 genes
translational attenuation, TAS1 genes
toxin metabolism, ISS1 genes
trans-Golgi network transport vesicle membrane, IDA1 genes
thiamin transporter activity, TAS1 genes
thyroid hormone transporter activity, NR1 genes
tubulin binding, NAS1 genes
toxin binding, NAS1 genes
thiamin transport, NAS1 genes
tRNA catabolism, IDA1 genes
translation release factor activity, codon specific, IEA1 genes
transcriptional repressor activity, IEP1 genes
transcriptional repressor activity, IMP1 genes
transferase activity, TAS1 genes
transferase activity, transferring glycosyl groups, ISS1 genes
transferase activity, transferring glycosyl groups, NAS1 genes
transcriptional repressor complex, NAS1 genes
tubulin-specific chaperone activity, IEA1 genes
tubulin-specific chaperone activity, TAS1 genes
tripeptidyl-peptidase I activity, IEA1 genes
transmission of nerve impulse, NAS1 genes
triacylglycerol biosynthesis, IDA1 genes
trans-Golgi network transport vesicle, IDA1 genes
troponin C binding, NAS1 genes
T-cell differentiation, IDA1 genes
T-cell differentiation, ISS1 genes
trypsin inhibitor activity, IMP1 genes
trypsin inhibitor activity, NAS1 genes
trypsin inhibitor activity, TAS1 genes
translation repressor activity, NAS1 genes
TPR domain binding, ISS1 genes
T-helper 1 type immune response, IC1 genes
T-helper 1 type immune response, IDA1 genes
T-helper 1 type immune response, NAS1 genes
T-helper 1 type immune response, TAS1 genes
T-helper cell differentiation, IDA1 genes
T-cell proliferation, NAS1 genes
T-cell receptor complex, TAS1 genes
T-cell activation, IMP1 genes
tissue regeneration, IEA1 genes
tissue regeneration, NAS1 genes
triacylated lipoprotein binding, ISS1 genes
T-cell receptor binding, IDA1 genes
tRNA 3'-processing, IDA1 genes
TAP complex, ISS1 genes
tyrosine phosphorylation of JAK2 protein, ISS1 genes
tyrosine phosphorylation of JAK2 protein, NAS1 genes
T-cell homeostasis, NAS1 genes
T-cell selection, NAS1 genes
T-cell selection, TAS1 genes
thymic T-cell selection, IDA1 genes
translation regulator activity, IEA1 genes
tricarboxylic acid cycle enzyme complex, IEA1 genes
thymocyte differentiation, ISS1 genes
tetrahydrofolate metabolism, IEA1 genes
TAP1 binding, ISS1 genes
TAP1 binding, TAS1 genes
TAP2 binding, IPI1 genes
TAP2 binding, TAS1 genes
tapasin binding, IPI1 genes
tapasin binding, ISS1 genes
tau protein binding, ISS1 genes
tau protein binding, TAS1 genes
tau-protein kinase activity, IDA1 genes
thiamin-triphosphatase activity, IDA1 genes
testosterone 6-beta-hydroxylase activity, IDA1 genes
AS3D: Alternative Splicing Structural Genomics Projects
CARB/UMBI